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Gene · 22919

MAPRE1: microtubule associated protein RP/EB family member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MAPRE1: microtubule associated protein RP/EB family member 1. Genes, record 22919. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/22919

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Gene

Symbol
MAPRE1
HGNC
Name
microtubule associated protein RP/EB family member 1
HGNC
NCBI Gene ID
22919
NCBI Gene
HGNC ID
HGNC:6890
HGNC
Ensembl
ENSG00000101367
NCBI Gene
Aliases
EB1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15691Microtubule-associated protein RP/EB family member 126833Ensembl, GeneID, HGNC

Source UniProt

Patents48

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453591Q15691Espacenet
EP 4650780 A22025-11-199653Q15691Espacenet
JP 2025517970 A2025-06-129653Q15691Espacenet
JP 2025081525 A2025-05-27302Q15691Espacenet
US 11892452 B22024-02-0666Q15691Espacenet
US 11860162 B22024-01-021348Q15691Espacenet
US 11446398 B22022-09-2051566Q15691Espacenet
JP 2022524081 A2022-04-27154537Q15691Espacenet
JP 2022521049 A2022-04-05493Q15691Espacenet
US 11078247 B22021-08-036585Q15691Espacenet

1 to 10 of 48

See all 48 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,581

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMAPRE1 papersNewest fiscal year
R35GM119552Biophysical Principles of Microtubule Dynamics92025
P30CA008748Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant72025
R01GM085115Mechanisms that control neuronal microtubule polarity72025
T32CA119925Integrated Biological Systems Training in Oncology72025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center62025
P40OD018537Bloomington Drosophila Stock Center at Indiana University52025
R01AR041836Function of Desmoglein 1/Pemphigus Foliaceus Antigen52025
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health52025
ZIACL080017IQGAP1 in tumorigenesis52025

1 to 10 of 1,581Source NIH's project files

See all 1,581 nih grants

Papers2,275

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ADNP Functions During Early Brain Development and Their Relevance to ASD and ADNP Syndrome.Int J Mol Sci202642450350PubTator, text miningPubMed
CLASP2 promotes repair of kinesin-1 damage to the microtubule lattice.bioRxiv202642427661PubTator, text miningPubMed
Dysregulation of the Tau-Microtubule-End-Binding Protein Axis in Alzheimer's Disease and Related Tauopathies.Int J Mol Sci202642353182PubTator, text miningPubMed
Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus.Analyst202642312723PubTator, text miningPubMed
Tubulin flux at spastin-induced nanodamage sites regulates microtubule rescue frequency and EB1 lifetimes.Proc Natl Acad Sci U S A202642190000PubTator, text miningPubMed
Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines.Proc Natl Acad Sci U S A202642044343PubTator, text miningPubMed
Relationship between urinary phytoestrogen metabolites and telomere length: a cross-sectional study from the National Health and Nutrition Examination Survey.Br J Nutr202641919341PubTator, text miningPubMed
Serum neurofilament light chain in hydrocephalus and surgical controls: baseline comparison and 24-hour perioperative dynamics under general anesthesia.Neurosurg Rev202641915252PubTator, text miningPubMed
The dynamics of podosomes, extracellular matrix-associated proteins regulate the cytoskeletal remodeling, mechanosensing, migration in Tau.Adv Protein Chem Struct Biol202641904004PubTator, text miningPubMed
The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets.Cells202641892342PubTator, text miningPubMed

1 to 10 of 2,275

See all 2,275 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/22919

GET https://conductscience.org/api/genes/v1/22919/patents?page=2