Gene · 22925
PLA2R1: phospholipase A2 receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PLA2R1: phospholipase A2 receptor 1. Genes, record 22925. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/22925
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13018 | Secretory phospholipase A2 receptor | 1,463 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents67
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026527559 A | 2026-08-14 | 14 | Q13018 | Espacenet |
| JP 2026526573 A | 2026-08-07 | 14 | Q13018 | Espacenet |
| EP 4753742 A2 | 2026-06-10 | 14 | Q13018 | Espacenet |
| EP 4754146 A1 | 2026-06-10 | 14 | Q13018 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 57879 | Q13018 | Espacenet |
| JP 2025541179 A | 2025-12-18 | 27 | Q13018 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3197 | Q13018 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2763 | Q13018 | Espacenet |
| EP 4630459 A1 | 2025-10-15 | 27 | Q13018 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10476 | Q13018 | Espacenet |
1 to 10 of 67
See all 67 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants591
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PLA2R1 papers | Newest fiscal year |
|---|---|---|---|
| K24AI130263 | Immunopathology of Indirect Airway Hyperresponsiveness in Asthma | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| R01DK076690 | Complement-mediated injury of the kidney: New mechanisms and novel therapies | 3 | 2025 |
| R01DK105124 | Genetics of IgA nephropathy by integrative network-based association studies | 3 | 2025 |
| U01DK100876 | The Columbia PCC for CureGN: the Cure Glomerulonephropathy network | 3 | 2025 |
| ZIACL090034 | Mechanisms of Pain and Immune Processes | 3 | 2025 |
| ZIADE000704 | Clinical and Mechanistic Investigations of Salivary Gland Dysfunction | 3 | 2025 |
| P20GM113226 | Hepatobiology and Toxicology COBRE | 2 | 2025 |
1 to 10 of 591Source NIH's project files
See all 591 nih grantsPapers2,349
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| LAMA5 pathogenic variant uncovers a novel autoantigen in membranous nephropathy. | Genes Dis | 2027 | 42763546 | PubTator, text mining | PubMed |
| Diagnostic pitfall: NSAID-induced membranous nephropathy with PLA2R positivity, IgG1-predominant deposits, C1q positivity, and concurrent acute interstitial nephritis-A case report. | Clin Chim Acta | 2027 | 42503368 | PubTator, text mining | PubMed |
| Rituximab Outcomes and Predictors of Treatment Failure in Primary Membranous Nephropathy: A Retrospective Cohort Study. | J Clin Med | 2026 | 42795840 | PubTator, text mining | PubMed |
| The role of serum BAFF, CFB, MCP-1 and anti-PLA2R antibodies in the efficacy evaluation of patients with membranous nephropathy. | J Med Biochem | 2026 | 42781234 | PubTator, text mining | PubMed |
| Risk prediction of PLA2R-Ab-negative membranous nephropathy: an interpretable multicenter machine learning model. | Front Immunol | 2026 | 42746065 | PubTator, text mining | PubMed |
| Anti-PLA2R autoantibodies induce complement activation via IgG subclass-dependent epitope pairings in membranous nephropathy. | J Clin Invest | 2026 | 42709482 | PubTator, text mining | PubMed |
| From immune dysregulation to renal injury: mechanistic insights and translational opportunities in immune-mediated nephropathies. | Front Cell Dev Biol | 2026 | 42707564 | PubTator, text mining | PubMed |
| Histopathological predictors of renal outcomes in idiopathic membranous nephropathy with a focus on global sclerotic glomeruli ratio. | Sci Rep | 2026 | 42706286 | PubTator, text mining | PubMed |
| An unusual presentation of membranous nephropathy with primary and secondary features: a case report. | BMC Nephrol | 2026 | 42687155 | PubTator, text mining | PubMed |
| Comparison of efficacy and safety among four therapeutic regimens in primary membranous nephropathy with high anti-PLA2R antibody titers: a single-center retrospective cohort study. | BMC Nephrol | 2026 | 42687143 | PubTator, text mining | PubMed |
1 to 10 of 2,349
See all 2,349 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/22925
GET https://conductscience.org/api/genes/v1/22925/patents?page=2