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Gene · 2294

FOXF1: forkhead box F1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FOXF1: forkhead box F1. Genes, record 2294. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2294

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Gene

Symbol
FOXF1
HGNC
Name
forkhead box F1
HGNC
NCBI Gene ID
2294
NCBI Gene
HGNC ID
HGNC:3809
HGNC
Ensembl
ENSG00000103241
NCBI Gene
Aliases
ACDMPV, FKHL5, FREAC1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q12946Forkhead box protein F13790Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-0614991Q12946Espacenet
JP 2025028160 A2025-02-2814991Q12946Espacenet
KR 1020250010750 A2025-01-2114991Q12946Espacenet
JP 2024109657 A2024-08-1414830Q12946Espacenet
JP 2024503719 A2024-01-26149Q12946Espacenet
US 11446398 B22022-09-2032543Q12946Espacenet
JP 2022524081 A2022-04-27135514Q12946Espacenet
JP 2021536249 A2021-12-2715184Q12946Espacenet
US 11078247 B22021-08-034141Q12946Espacenet
JP 2021507703 A2021-02-2515144Q12946Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,260

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFOXF1 papersNewest fiscal year
R01HL141174Transcriptional Regulation of Endothelial Cells after Neonatal Lung Injury192025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease112025
R01HL152973Development of novel therapeutic approaches for treatment of Alveolar Capillary Dysplasia92025
P01HD093363CLEAR Consortium: Discovering the Developmental Mechanisms of Trachea-Esophageal Birth Defects62025
R24HD000836Laboratory of Developmental Biology52025
P30ES010126UNC Center for Environmental Health and Susceptibility42025
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025

1 to 10 of 1,260Source NIH's project files

See all 1,260 nih grants

Papers1,430

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Combination of Blastocyst Complementation and Omics Allows Fast Evaluation of Human Pathogenic Mutations in Mice.Am J Respir Cell Mol Biol202642814875PubTator, text miningPubMed
Survival Into Adulthood With FOXF1-Associated Pulmonary Vascular Disease After Neonatal Onset.Pulm Circ202642540458PubTator, text miningPubMed
Vessel Organoids Reveal FOXF1 Variant-Specific Regulation of Mesoderm and Capillary Development.bioRxiv202642523355PubTator, text miningPubMed
Intestine organotypic culture recapitulates human embryonic villus morphogenesis at week 8.Tissue Barriers202642458784PubTator, text miningPubMed
Prenatal Presentation of Congenital Alveolar Capillary Dysplasia With Misalignment of Pulmonary Veins: A Case Initially Suspected as Posterior Urethral Valves.J Paediatr Child Health202642434910PubTator, text miningPubMed
Molecular-Genetic Basis of Pulmonary Arterial Hypertension (PAH).Curr Issues Mol Biol202642353577PubTator, text miningPubMed
DNA Methylation at Birth Showing Age-Specific Association with Atopy in Children: A Prospective Longitudinal Study.Epigenomes202642346028PubTator, text miningPubMed
KLF4/FOXF1 axis alleviates silicosis fibrosis by modulating fibroblast behavior and extracellular matrix remodeling.J Environ Sci (China)202642336549PubTator, text miningPubMed
[Research on 5-Fluorouracil-Induced Injury in Human Intestinal Organoids].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642227455PubTator, text miningPubMed
Small partial deletion of a highly GC-rich FOXF1 exon 1 in two deceased siblings with alveolar capillary dysplasia.Genomics202642097522PubTator, text miningPubMed

1 to 10 of 1,430

See all 1,430 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2294

GET https://conductscience.org/api/genes/v1/2294/patents?page=2