Gene · 2294
FOXF1: forkhead box F1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FOXF1: forkhead box F1. Genes, record 2294. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2294
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q12946 | Forkhead box protein F1 | 379 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents22
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 14991 | Q12946 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14991 | Q12946 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14991 | Q12946 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14830 | Q12946 | Espacenet |
| JP 2024503719 A | 2024-01-26 | 149 | Q12946 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 32543 | Q12946 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 135514 | Q12946 | Espacenet |
| JP 2021536249 A | 2021-12-27 | 15184 | Q12946 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 4141 | Q12946 | Espacenet |
| JP 2021507703 A | 2021-02-25 | 15144 | Q12946 | Espacenet |
1 to 10 of 22
See all 22 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,260
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FOXF1 papers | Newest fiscal year |
|---|---|---|---|
| R01HL141174 | Transcriptional Regulation of Endothelial Cells after Neonatal Lung Injury | 19 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 11 | 2025 |
| R01HL152973 | Development of novel therapeutic approaches for treatment of Alveolar Capillary Dysplasia | 9 | 2025 |
| P01HD093363 | CLEAR Consortium: Discovering the Developmental Mechanisms of Trachea-Esophageal Birth Defects | 6 | 2025 |
| R24HD000836 | Laboratory of Developmental Biology | 5 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 4 | 2025 |
| R01DK072381 | Kidney Injury Molecule-1 in Epithelial Repair | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,260Source NIH's project files
See all 1,260 nih grantsPapers1,430
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Combination of Blastocyst Complementation and Omics Allows Fast Evaluation of Human Pathogenic Mutations in Mice. | Am J Respir Cell Mol Biol | 2026 | 42814875 | PubTator, text mining | PubMed |
| Survival Into Adulthood With FOXF1-Associated Pulmonary Vascular Disease After Neonatal Onset. | Pulm Circ | 2026 | 42540458 | PubTator, text mining | PubMed |
| Vessel Organoids Reveal FOXF1 Variant-Specific Regulation of Mesoderm and Capillary Development. | bioRxiv | 2026 | 42523355 | PubTator, text mining | PubMed |
| Intestine organotypic culture recapitulates human embryonic villus morphogenesis at week 8. | Tissue Barriers | 2026 | 42458784 | PubTator, text mining | PubMed |
| Prenatal Presentation of Congenital Alveolar Capillary Dysplasia With Misalignment of Pulmonary Veins: A Case Initially Suspected as Posterior Urethral Valves. | J Paediatr Child Health | 2026 | 42434910 | PubTator, text mining | PubMed |
| Molecular-Genetic Basis of Pulmonary Arterial Hypertension (PAH). | Curr Issues Mol Biol | 2026 | 42353577 | PubTator, text mining | PubMed |
| DNA Methylation at Birth Showing Age-Specific Association with Atopy in Children: A Prospective Longitudinal Study. | Epigenomes | 2026 | 42346028 | PubTator, text mining | PubMed |
| KLF4/FOXF1 axis alleviates silicosis fibrosis by modulating fibroblast behavior and extracellular matrix remodeling. | J Environ Sci (China) | 2026 | 42336549 | PubTator, text mining | PubMed |
| [Research on 5-Fluorouracil-Induced Injury in Human Intestinal Organoids]. | Zhongguo Shi Yan Xue Ye Xue Za Zhi | 2026 | 42227455 | PubTator, text mining | PubMed |
| Small partial deletion of a highly GC-rich FOXF1 exon 1 in two deceased siblings with alveolar capillary dysplasia. | Genomics | 2026 | 42097522 | PubTator, text mining | PubMed |
1 to 10 of 1,430
See all 1,430 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2294
GET https://conductscience.org/api/genes/v1/2294/patents?page=2