Gene · 23019
CNOT1: CCR4-NOT transcription complex subunit 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CNOT1: CCR4-NOT transcription complex subunit 1. Genes, record 23019. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23019
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| A5YKK6 | CCR4-NOT transcription complex subunit 1 | 2,376 | 21 | Ensembl, GeneID, HGNC |
Source UniProt
Patents19
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 40386 | A5YKK6 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5349 | A5YKK6 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4939 | A5YKK6 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1061 | A5YKK6 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1061 | A5YKK6 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4939 | A5YKK6 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5349 | A5YKK6 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 12741 | A5YKK6 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4199 | A5YKK6 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 115712 | A5YKK6 | Espacenet |
1 to 10 of 19
See all 19 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,460
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CNOT1 papers | Newest fiscal year |
|---|---|---|---|
| ZIAES090080 | TTP and related proteins in the regulation of gene expression | 11 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 5 | 2025 |
| ZICES043010 | Computational Chemistry and Macromolecular Modeling | 5 | 2025 |
| ZIABC011977 | Molecular Mechanisms of mRNA Regulation and Decay | 4 | 2025 |
| ZIAES102745 | Role of Pluripotency Factors in Pluripotent Stem Cells, Development and Disease | 4 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,460Source NIH's project files
See all 1,460 nih grantsPapers1,427
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Deadenylation and decapping factors cooperatively stimulate biochemical activities of DEAD-box ATPase Dhh1. | Nucleic Acids Res | 2026 | 42755361 | PubTator, text mining | PubMed |
| Expanding the Genotypic and Phenotypic Spectrum of Vissers-Bodmer Syndrome. | Am J Med Genet A | 2026 | 42686658 | PubTator, text mining | PubMed |
| Deadenylation and Decapping Factors Cooperatively Stimulate Biochemical Activities of DEAD-Box ATPase Dhh1. | bioRxiv | 2026 | 42388790 | PubTator, text mining | PubMed |
| CCR4-NOT is required for suppressing pervasive transcription and retrotransposable elements. | J Biol Chem | 2026 | 42336285 | PubTator, text mining | PubMed |
| A BRRF1-CCR4-NOT axis underlies conserved transcriptome-wide loss of splicing fidelity during gammaherpesvirus reactivation. | bioRxiv | 2026 | 42239063 | PubTator, text mining | PubMed |
| Modeling patient variants of Cnot1 and Cdc42bpb results in distinct forms of congenital diaphragmatic hernia in mice. | bioRxiv | 2026 | 42124667 | PubTator, text mining | PubMed |
| m1A-mediated regulation of BIRC2 mRNA stability drives apoptosis evasion and tumor progression in liver cancer. | Cell Death Dis | 2026 | 41991508 | PubTator, text mining | PubMed |
| RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation. | Nucleic Acids Res | 2026 | 41914497 | PubTator, text mining | PubMed |
| Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor Progression. | Cells | 2026 | 41892292 | PubTator, text mining | PubMed |
| Degron models: a toolbox for rapid in vivo depletion of essential proteins regulating mRNA metabolism. | Commun Biol | 2026 | 41851445 | PubTator, text mining | PubMed |
1 to 10 of 1,427
See all 1,427 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23019
GET https://conductscience.org/api/genes/v1/23019/patents