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Gene · 23019

CNOT1: CCR4-NOT transcription complex subunit 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CNOT1: CCR4-NOT transcription complex subunit 1. Genes, record 23019. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23019

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Gene

Symbol
CNOT1
HGNC
Name
CCR4-NOT transcription complex subunit 1
HGNC
NCBI Gene ID
23019
NCBI Gene
HGNC ID
HGNC:7877
HGNC
Ensembl
ENSG00000125107
NCBI Gene
Aliases
AD-005, CDC39, HPE12, KIAA1007, NOT1, NOT1H, VIBOS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
A5YKK6CCR4-NOT transcription complex subunit 12,37621Ensembl, GeneID, HGNC

Source UniProt

Patents19

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440386A5YKK6Espacenet
EP 4650780 A22025-11-195349A5YKK6Espacenet
EP 4641201 A22025-10-294939A5YKK6Espacenet
JP 2025529142 A2025-09-041061A5YKK6Espacenet
US 12371689 B22025-07-291061A5YKK6Espacenet
JP 2025517969 A2025-06-124939A5YKK6Espacenet
JP 2025517970 A2025-06-125349A5YKK6Espacenet
US 11446398 B22022-09-2012741A5YKK6Espacenet
US 11400116 B22022-08-024199A5YKK6Espacenet
JP 2022524081 A2022-04-27115712A5YKK6Espacenet

1 to 10 of 19

See all 19 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,460

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCNOT1 papersNewest fiscal year
ZIAES090080TTP and related proteins in the regulation of gene expression112025
P30DK063491Diabetes Research Center (DRC)52025
ZICES043010Computational Chemistry and Macromolecular Modeling52025
ZIABC011977Molecular Mechanisms of mRNA Regulation and Decay42025
ZIAES102745Role of Pluripotency Factors in Pluripotent Stem Cells, Development and Disease42025
P30AI027763UCSF-Bay Area Center for AIDS Research32025
P30CA015704Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA046934University of Colorado Cancer Center Support Grant32025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025

1 to 10 of 1,460Source NIH's project files

See all 1,460 nih grants

Papers1,427

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Deadenylation and decapping factors cooperatively stimulate biochemical activities of DEAD-box ATPase Dhh1.Nucleic Acids Res202642755361PubTator, text miningPubMed
Expanding the Genotypic and Phenotypic Spectrum of Vissers-Bodmer Syndrome.Am J Med Genet A202642686658PubTator, text miningPubMed
Deadenylation and Decapping Factors Cooperatively Stimulate Biochemical Activities of DEAD-Box ATPase Dhh1.bioRxiv202642388790PubTator, text miningPubMed
CCR4-NOT is required for suppressing pervasive transcription and retrotransposable elements.J Biol Chem202642336285PubTator, text miningPubMed
A BRRF1-CCR4-NOT axis underlies conserved transcriptome-wide loss of splicing fidelity during gammaherpesvirus reactivation.bioRxiv202642239063PubTator, text miningPubMed
Modeling patient variants of Cnot1 and Cdc42bpb results in distinct forms of congenital diaphragmatic hernia in mice.bioRxiv202642124667PubTator, text miningPubMed
m1A-mediated regulation of BIRC2 mRNA stability drives apoptosis evasion and tumor progression in liver cancer.Cell Death Dis202641991508PubTator, text miningPubMed
RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation.Nucleic Acids Res202641914497PubTator, text miningPubMed
Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor Progression.Cells202641892292PubTator, text miningPubMed
Degron models: a toolbox for rapid in vivo depletion of essential proteins regulating mRNA metabolism.Commun Biol202641851445PubTator, text miningPubMed

1 to 10 of 1,427

See all 1,427 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/23019

GET https://conductscience.org/api/genes/v1/23019/patents