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KDM1A: lysine demethylase 1A

1 protein, 74 patents, 1 drug, 14 trials, 4,184 NIH grants and 7,800 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolKDM1AHGNC
Namelysine demethylase 1AHGNC
NCBI Gene ID23028NCBI Gene
HGNC IDHGNC:29079HGNC
EnsemblENSG00000004487NCBI Gene
AliasesAIMAH3, AOF2, BHC110, CPRF, KDM1, KIAA0601, LSD1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O60341Lysine-specific histone demethylase 1A852129Ensembl, GeneID, HGNCUniProt

Patents 74

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452064O60341Espacenet
EP 4650780 A22025-11-197323O60341Espacenet
EP 4641201 A22025-10-297272O60341Espacenet
JP 2025147176 A2025-10-067412O60341Espacenet
JP 2025531268 A2025-09-19247O60341Espacenet
JP 2025529142 A2025-09-046804O60341Espacenet
US 12398394 B22025-08-26606O60341Espacenet
US 12398406 B22025-08-2683O60341Espacenet
JP 2025527567 A2025-08-22606O60341Espacenet
JP 2025524469 A2025-07-30225O60341Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BOMEDEMSTATCHEMBL4297289Lysine-specific histone demethylase 1 inhibitorINHIBITORChEMBL

Trials 14

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07424950BOMEDEMSTATPHASE2ClinicalTrials.gov
NCT06456346BOMEDEMSTATPHASE3ClinicalTrials.gov
NCT06351631BOMEDEMSTATPHASE3ClinicalTrials.gov
NCT06079879BOMEDEMSTATPHASE3ClinicalTrials.gov
NCT05597306BOMEDEMSTATPHASE1ClinicalTrials.gov
NCT05569538BOMEDEMSTATPHASE2ClinicalTrials.gov
NCT05558696BOMEDEMSTATPHASE2ClinicalTrials.gov
NCT05223920BOMEDEMSTATPHASE22025-09-22ClinicalTrials.gov
NCT05191797BOMEDEMSTATPHASE1/PHASE22024-09-26ClinicalTrials.gov
NCT04262141BOMEDEMSTATPHASE2ClinicalTrials.gov

NIH grants 4184

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant502,025NIH's project files
P30CA016672Cancer Center Support Grant502,025NIH's project files
P50CA097186The Pacific Northwest Prostate Cancer SPORE182,025NIH's project files
P30CA042014Cancer Center Support Grant172,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program142,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant142,025NIH's project files
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer132,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028122,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA122,025NIH's project files
P30CA006973Regional Oncology Research Center112,025NIH's project files

Papers 7800

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827376PubTator, text miningPubMed
42823199PubTator, text miningPubMed
42809184PubTator, text miningPubMed
42805446PubTator, text miningPubMed
42794887PubTator, text miningPubMed
42792755PubTator, text miningPubMed
42747230PubTator, text miningPubMed
42715072PubTator, text miningPubMed
42695563PubTator, text miningPubMed
42692917PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license