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Gene · 23082

PPRC1: PPARG related coactivator 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PPRC1: PPARG related coactivator 1. Genes, record 23082. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23082

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Gene

Symbol
PPRC1
HGNC
Name
PPARG related coactivator 1
HGNC
NCBI Gene ID
23082
NCBI Gene
HGNC ID
HGNC:30025
HGNC
Ensembl
ENSG00000148840
NCBI Gene
Aliases
KIAA0595, MGC74642, PRC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q5VV67Peroxisome proliferator-activated receptor gamma coactivator-related protein 11,6640Ensembl, GeneID, HGNC

Source UniProt

Patents18

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193007Q5VV67Espacenet
EP 4641201 A22025-10-292582Q5VV67Espacenet
JP 2025517969 A2025-06-122582Q5VV67Espacenet
JP 2025517970 A2025-06-123007Q5VV67Espacenet
US 11446398 B22022-09-2062171Q5VV67Espacenet
JP 2022524081 A2022-04-27165142Q5VV67Espacenet
US 11136562 B22021-10-05285Q5VV67Espacenet
JP 2019033757 A2019-03-0723904Q5VV67Espacenet
EP 3399991 A12018-11-14285Q5VV67Espacenet
KR 1020180096788 A2018-08-29285Q5VV67Espacenet

1 to 10 of 18

See all 18 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,053

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePPRC1 papersNewest fiscal year
R01CA163915ATP-Dependent Chromatin Remodeling in Human Malignancy62025
P30CA016672Cancer Center Support Grant42025
R01EY010804Setting the Stage for Replacement of Mitochondrial Genes42025
T32CA009138Molecular, Genetic and Cellular Targets of Cancer Training Program42025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA062203Cancer Center Support Grant32025
P30DK056341Washington University Nutrition Obesity Research Center32025
ZIAHL005801Genome-wide analysis of chromatin modifications32025
P01AG052350Vascular Contributions to Dementia and Genetic Risk Factors for Alzheimer's Disease22025
P01CA019014Viral Oncogenesis, Latency, and Replication22025

1 to 10 of 1,053Source NIH's project files

See all 1,053 nih grants

Papers1,316

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The prc gene as a high-resolution proxy for Aeromonas genus-wide clonal genealogy, phylogenomic validation and superiority over traditional MLST.Sci Rep202642661048PubTator, text miningPubMed
Establishment, biobanking, and multi-omics characterization of 41 patient-derived colorectal cancer organoids: MYC/PRC classification.Transl Oncol202642349318PubTator, text miningPubMed
WSTF deficiency reprograms regulatory networks by linking locus-specific chromatin remodeling to altered isoform expression and misdirected signaling.Nucleic Acids Res202642258541PubTator, text miningPubMed
Combinatorial pioneer transcription factor binding reinforces bivalent epigenetic states to preserve lineage fidelity.bioRxiv202642239318PubTator, text miningPubMed
Targeting the Polycomb repressive complexes in hepatocellular carcinoma: A comprehensive and updated analysis of mechanistic insights and clinical application.Biochim Biophys Acta Rev Cancer202641967817PubTator, text miningPubMed
Genome architecture: nuclear context links noncoding variants to transcriptional programs.Signal Transduct Target Ther202641826337PubTator, text miningPubMed
Heterogeneity and Regulatory Mechanisms of ALK-Mutant and Wild-Type Epithelial Cells in Non-Small-Cell Lung Cancer: Single-Cell Transcriptomics and Chromatin Accessibility.Pharmacology202641818350PubTator, text miningPubMed
PPRC1 is a prognostic biomarker and key regulator of mitochondrial oxidative phosphorylation in multiple myeloma.Ann Med202641814677PubTator, text miningPubMed
Mechanobiology of the Nucleolus.Biol Cell202641761918PubTator, text miningPubMed
Weight Loss by Diet Versus Metabolic Surgery Increases Circulating NT-proANP in Obese Individuals.J Clin Med202641753203PubTator, text miningPubMed

1 to 10 of 1,316

See all 1,316 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/23082

GET https://conductscience.org/api/genes/v1/23082/patents