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Gene · 23118

TAB2: TGF-beta activated kinase 1 (MAP3K7) binding protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TAB2: TGF-beta activated kinase 1 (MAP3K7) binding protein 2. Genes, record 23118. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23118

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Gene

Symbol
TAB2
HGNC
Name
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
HGNC
NCBI Gene ID
23118
NCBI Gene
HGNC ID
HGNC:17075
HGNC
Ensembl
ENSG00000055208
NCBI Gene
Aliases
CHTD2, KIAA0733, MAP3K7IP2, TAB-2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NYJ8TGF-beta-activated kinase 1 and MAP3K7-binding protein 26936Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466904Q9NYJ8Espacenet
JP 2026004568 A2026-01-1466905Q9NYJ8Espacenet
JP 2026004568 A2026-01-1466908Q9NYJ8Espacenet
EP 4641201 A22025-10-298405Q9NYJ8Espacenet
JP 2025524002 A2025-07-2524Q9NYJ8Espacenet
JP 2025517969 A2025-06-128405Q9NYJ8Espacenet
KR 1020250039465 A2025-03-2024Q9NYJ8Espacenet
JP 2024023699 A2024-02-2124Q9NYJ8Espacenet
JP 2024505890 A2024-02-0824Q9NYJ8Espacenet
JP 2023509886 A2023-03-1024Q9NYJ8Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,173

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTAB2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
R35GM127121Cell signaling by G protein-coupled receptors52025
R01AI060025From Drosophila Immunity to Anti-Inflammatories42025
K12GM068524San Diego IRACDA Scholars Program32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30CA016058Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
P30CA072720Cancer Center Support Grant32025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.22025
P30CA010815Consolidated Basic Cancer Research Program22025

1 to 10 of 1,173Source NIH's project files

See all 1,173 nih grants

Papers1,755

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Strained Os nanoclusters on TaB2 for alkaline hydrogen evolution through hydroxyl management and interfacial water restructuring.Chem Sci202642621414PubTator, text miningPubMed
Tumor-derived PTX3 drives an immunosuppressive myeloid landscape and inhibits CD8 T cell-mediated anti-tumor immunity via PI3K-dependent signaling.Oncogene202642618717PubTator, text miningPubMed
TAB2 Causes Neuronal Damage by Aggravating Microglia-Mediated Neuroinflammation in Parkinson's Disease.Adv Sci (Weinh)202642606072PubTator, text miningPubMed
Single-cell transcriptomics uncovers HPV-driven immune evasion and establishes a TAB2-based prognostic signature in cervical cancer.Transl Oncol202642551127PubTator, text miningPubMed
TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development.PLoS Biol202642550797PubTator, text miningPubMed
LncRNA-MSTRG.16919.1 regulates the proliferation of BHV-1 in MDBK cells through TAK1/TAB1/TAB2/TAB3 complexes.BMC Vet Res202642432683PubTator, text miningPubMed
Repair of Ventricular Septal Defect in Children with TAB2 Gene Anomalies and Associated Cardiomyopathy.Surg Case Rep202642327856PubTator, text miningPubMed
Cardiomyocyte programmed cell death in dilated cardiomyopathy: molecular crosstalk and therapeutic implications.Front Cell Dev Biol202642311507PubTator, text miningPubMed
Tribranched Multiblock Copolymers Mimicking the Molecular Claw Design in N-Type Conjugated Polymers for High-Yield Semiconducting Carbon Nanotube Sorting and Phototransistor Memory Applications.ACS Appl Mater Interfaces202642284118PubTator, text miningPubMed
Circadian gene CLOCK-mediated LLPS of NBR1 and p62/SQSTM1 inhibits proliferation and migration of nasopharyngeal carcinoma.Cell Death Dis202642270580PubTator, text miningPubMed

1 to 10 of 1,755

See all 1,755 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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