Gene · 23118
TAB2: TGF-beta activated kinase 1 (MAP3K7) binding protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TAB2: TGF-beta activated kinase 1 (MAP3K7) binding protein 2. Genes, record 23118. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23118
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NYJ8 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | 693 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 66904 | Q9NYJ8 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 66905 | Q9NYJ8 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 66908 | Q9NYJ8 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8405 | Q9NYJ8 | Espacenet |
| JP 2025524002 A | 2025-07-25 | 24 | Q9NYJ8 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8405 | Q9NYJ8 | Espacenet |
| KR 1020250039465 A | 2025-03-20 | 24 | Q9NYJ8 | Espacenet |
| JP 2024023699 A | 2024-02-21 | 24 | Q9NYJ8 | Espacenet |
| JP 2024505890 A | 2024-02-08 | 24 | Q9NYJ8 | Espacenet |
| JP 2023509886 A | 2023-03-10 | 24 | Q9NYJ8 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,173
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TAB2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| R35GM127121 | Cell signaling by G protein-coupled receptors | 5 | 2025 |
| R01AI060025 | From Drosophila Immunity to Anti-Inflammatories | 4 | 2025 |
| K12GM068524 | San Diego IRACDA Scholars Program | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30CA072720 | Cancer Center Support Grant | 3 | 2025 |
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 2 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 2 | 2025 |
1 to 10 of 1,173Source NIH's project files
See all 1,173 nih grantsPapers1,755
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Strained Os nanoclusters on TaB2 for alkaline hydrogen evolution through hydroxyl management and interfacial water restructuring. | Chem Sci | 2026 | 42621414 | PubTator, text mining | PubMed |
| Tumor-derived PTX3 drives an immunosuppressive myeloid landscape and inhibits CD8 T cell-mediated anti-tumor immunity via PI3K-dependent signaling. | Oncogene | 2026 | 42618717 | PubTator, text mining | PubMed |
| TAB2 Causes Neuronal Damage by Aggravating Microglia-Mediated Neuroinflammation in Parkinson's Disease. | Adv Sci (Weinh) | 2026 | 42606072 | PubTator, text mining | PubMed |
| Single-cell transcriptomics uncovers HPV-driven immune evasion and establishes a TAB2-based prognostic signature in cervical cancer. | Transl Oncol | 2026 | 42551127 | PubTator, text mining | PubMed |
| TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development. | PLoS Biol | 2026 | 42550797 | PubTator, text mining | PubMed |
| LncRNA-MSTRG.16919.1 regulates the proliferation of BHV-1 in MDBK cells through TAK1/TAB1/TAB2/TAB3 complexes. | BMC Vet Res | 2026 | 42432683 | PubTator, text mining | PubMed |
| Repair of Ventricular Septal Defect in Children with TAB2 Gene Anomalies and Associated Cardiomyopathy. | Surg Case Rep | 2026 | 42327856 | PubTator, text mining | PubMed |
| Cardiomyocyte programmed cell death in dilated cardiomyopathy: molecular crosstalk and therapeutic implications. | Front Cell Dev Biol | 2026 | 42311507 | PubTator, text mining | PubMed |
| Tribranched Multiblock Copolymers Mimicking the Molecular Claw Design in N-Type Conjugated Polymers for High-Yield Semiconducting Carbon Nanotube Sorting and Phototransistor Memory Applications. | ACS Appl Mater Interfaces | 2026 | 42284118 | PubTator, text mining | PubMed |
| Circadian gene CLOCK-mediated LLPS of NBR1 and p62/SQSTM1 inhibits proliferation and migration of nasopharyngeal carcinoma. | Cell Death Dis | 2026 | 42270580 | PubTator, text mining | PubMed |
1 to 10 of 1,755
See all 1,755 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23118
GET https://conductscience.org/api/genes/v1/23118/patents?page=2