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FLG: filaggrin

1 protein, 108 patents, 0 drugs, 0 trials, 2,149 NIH grants and 7,091 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFLGHGNC
NamefilaggrinHGNC
NCBI Gene ID2312NCBI Gene
HGNC IDHGNC:3748HGNC
EnsemblENSG00000143631NCBI Gene
AliasesATOD2, FLG-1, FLG1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P20930Filaggrin4,0611Ensembl, GeneID, HGNCUniProt

Patents 108

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026082974 A2026-05-19120P20930Espacenet
US 12569521 B22026-03-101P20930Espacenet
US 12569521 B22026-03-1011P20930Espacenet
JP 2026004568 A2026-01-1446339P20930Espacenet
EP 4650780 A22025-11-198506P20930Espacenet
KR 1028860230000 A2025-11-108P20930Espacenet
EP 4640849 A22025-10-291282P20930Espacenet
EP 4641201 A22025-10-298669P20930Espacenet
JP 2025107990 A2025-07-2252P20930Espacenet
JP 2025519096 A2025-06-241282P20930Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2149

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
U19AI070235Epithelial Genes in Allergic Inflammation452,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease262,025NIH's project files
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center162,025NIH's project files
T32AR007465Penn Dermatology Research Training Program122,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success112,025NIH's project files
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis102,025NIH's project files
R01AR066530Regulators of epidermal growth and differentiation92,025NIH's project files
ZIAHG000180Gene-Environment Interactions at the Skin Surface92,025NIH's project files
P30AR069589Penn Skin Biology and Diseases Resource-based Center82,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center82,025NIH's project files

Papers 7091

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823874PubTator, text miningPubMed
42813198PubTator, text miningPubMed
42812956PubTator, text miningPubMed
42805066PubTator, text miningPubMed
42800590PubTator, text miningPubMed
42789100PubTator, text miningPubMed
42778843PubTator, text miningPubMed
42776206PubTator, text miningPubMed
42749005PubTator, text miningPubMed
42732409PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license