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FLI1: Fli-1 proto-oncogene, ETS transcription factor

1 protein, 74 patents, 0 drugs, 0 trials, 3,122 NIH grants and 6,218 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFLI1HGNC
NameFli-1 proto-oncogene, ETS transcription factorHGNC
NCBI Gene ID2313NCBI Gene
HGNC IDHGNC:3749HGNC
EnsemblENSG00000151702NCBI Gene
AliasesBDPLT21, EWSR2, FLI-1, SIC-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q01543Friend leukemia integration 1 transcription factor45214Ensembl, GeneID, HGNCUniProt

Patents 74

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446699Q01543Espacenet
US 12486300 B22025-12-023Q01543Espacenet
EP 4650780 A22025-11-1915608Q01543Espacenet
JP 2025147176 A2025-10-0614968Q01543Espacenet
JP 2025517970 A2025-06-1215608Q01543Espacenet
JP 2025032204 A2025-03-1128491Q01543Espacenet
JP 2025028160 A2025-02-2814968Q01543Espacenet
EP 4511478 A22025-02-263Q01543Espacenet
KR 1020250010750 A2025-01-2114968Q01543Espacenet
US 12146165 B22024-11-192Q01543Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3122

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1022,025NIH's project files
P30CA016672Cancer Center Support Grant442,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)282,025NIH's project files
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant262,025NIH's project files
P30CA042014Cancer Center Support Grant252,025NIH's project files
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement192,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant162,025NIH's project files
P50CA217694SPORE in Soft Tissue Sarcoma162,025NIH's project files
U10CA180899Children's Oncology Group Statistics and Data Center152,025NIH's project files
P30CA016058Cancer Center Support Grant132,025NIH's project files

Papers 6218

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42791051PubTator, text miningPubMed
42789362PubTator, text miningPubMed
42783200PubTator, text miningPubMed
42780001PubTator, text miningPubMed
42762293PubTator, text miningPubMed
42762264PubTator, text miningPubMed
42698478PubTator, text miningPubMed
42698421PubTator, text miningPubMed
42681974PubTator, text miningPubMed
42675859PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license