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Gene · 23152

CIC: capicua transcriptional repressor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CIC: capicua transcriptional repressor. Genes, record 23152. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23152

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Gene

Symbol
CIC
HGNC
Name
capicua transcriptional repressor
HGNC
NCBI Gene ID
23152
NCBI Gene
HGNC ID
HGNC:14214
HGNC
Ensembl
ENSG00000079432
NCBI Gene
Aliases
KIAA0306, MRD45
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96RK0Protein capicua homolog2,5177Ensembl, GeneID, HGNC

Source UniProt

Patents0

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

None in this release.

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants775

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCIC papersNewest fiscal year
P30CA008748Cancer Center Support Grant572025
P50CA217694SPORE in Soft Tissue Sarcoma152025
P50CA097257Brain Tumor SPORE Grant132025
P30CA016672Cancer Center Support Grant122025
R01NS027699Molecular Studies of Spinocerebellar Ataxia Type 1112025
P30CA006973Regional Oncology Research Center102025
P50CA165962Targeted Therapies for Glioma52025
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN42025
P30CA034196Cancer Center Support (CORE) Grant42025
P50CA211015UCLA SPORE in Brain Cancer42025

1 to 10 of 775Source NIH's project files

See all 775 nih grants

Papers1,814

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dural CIC::DUX4 sarcoma presenting with intracranial hemorrhage at both initial diagnosis and recurrence: a case report and literature review.Brain Tumor Pathol202642816716PubTator, text miningPubMed
Neuromotor Compromise as a Presenting Symptom in Advanced Lower Extremity Soft Tissue Sarcoma: A Case Series.HCA Healthc J Med202642751661PubTator, text miningPubMed
Non-Meningothelial Mesenchymal Tumor of the Central Nervous System: Case Report and Literature Review.Neuropathology202642745692PubTator, text miningPubMed
Cerebrospinal fluid infection caused by Mixta calida in a patient with sarcoma: Case report with whole-genome sequencing.Indian J Med Microbiol202642731728PubTator, text miningPubMed
Undifferentiated round cell sarcoma with CIC::NUTM1 fusion: expanding the clinicopathologic spectrum of a rare molecular variant of CIC-rearranged sarcoma.Virchows Arch202642693277PubTator, text miningPubMed
Next-Generation Sequencing Refines Diagnosis and Expands Precision Medicine Opportunities in Soft Tissue Sarcomas.Int J Mol Sci202642653206PubTator, text miningPubMed
C1q CIC in Lupus Nephritis: An Analysis of 883 Patients.Int J Med Sci202642524383PubTator, text miningPubMed
AER-DCWGAN: Adversarial Encoder-Regularized Dual-Conditional Wasserstein GAN for Imbalanced Network Intrusion Detection.Sensors (Basel)202642515390PubTator, text miningPubMed
In silico evaluation of the role of PEA3 subfamily ETS transcription factors in chemoresistance in ovarian cancer.Turk J Med Sci202642499433PubTator, text miningPubMed
Isoform-paralog specificity and tissue-dependent vulnerabilities in neurological disorders.Genes Dev202642481419PubTator, text miningPubMed

1 to 10 of 1,814

See all 1,814 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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