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FLNA: filamin A

1 protein, 54 patents, 1 drug, 7 trials, 3,052 NIH grants and 5,130 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFLNAHGNC
Namefilamin AHGNC
NCBI Gene ID2316NCBI Gene
HGNC IDHGNC:3754HGNC
EnsemblENSG00000196924NCBI Gene
AliasesABP-280, ABPX, CSBS, CVD1, FGS2, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVDNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P21333Filamin-A2,64726Ensembl, GeneID, HGNCUniProt

Patents 54

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446349P21333Espacenet
EP 4650780 A22025-11-198681P21333Espacenet
EP 4641201 A22025-10-298869P21333Espacenet
JP 2025148560 A2025-10-073P21333Espacenet
KR 1020250117602 A2025-08-056P21333Espacenet
JP 2025517969 A2025-06-128869P21333Espacenet
JP 2025517970 A2025-06-128681P21333Espacenet
WO 2025032112 A12025-02-131P21333Espacenet
EP 4373841 A12024-05-291P21333Espacenet
KR 1020240009366 A2024-01-226P21333Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
SIMUFILAMCHEMBL4650230Filamin-A positive modulatorPOSITIVE MODULATORChEMBL

Trials 7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05575076SIMUFILAMPHASE32025-05-14ClinicalTrials.gov
NCT05352763SIMUFILAMPHASE22025-08-15ClinicalTrials.gov
NCT05026177SIMUFILAMPHASE32025-09-22ClinicalTrials.gov
NCT04994483SIMUFILAMPHASE32025-05-25ClinicalTrials.gov
NCT04388254SIMUFILAMPHASE22025-04-22ClinicalTrials.gov
NCT04079803SIMUFILAMPHASE22021-06-01ClinicalTrials.gov
NCT03748706SIMUFILAMPHASE22021-04-01ClinicalTrials.gov

NIH grants 3052

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant152,025NIH's project files
P30CA016672Cancer Center Support Grant102,025NIH's project files
R01HL085844Functional interactions of cardiac ion channels62,025NIH's project files
R37NS035129Human Epilepsy Genetics - Mosaic Mutations in Focal Epilepsy62,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award62,025NIH's project files
P30CA006973Regional Oncology Research Center52,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program52,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant52,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant52,025NIH's project files
P30CA071789University of Hawaii Cancer Center CCSG52,025NIH's project files

Papers 5130

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42810534PubTator, text miningPubMed
42790822PubTator, text miningPubMed
42761222PubTator, text miningPubMed
42751148PubTator, text miningPubMed
42737734PubTator, text miningPubMed
42731651PubTator, text miningPubMed
42707154PubTator, text miningPubMed
42695868PubTator, text miningPubMed
42683436PubTator, text miningPubMed
42677491PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license