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Gene · 2317

FLNB: filamin B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FLNB: filamin B. Genes, record 2317. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2317

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Gene

Symbol
FLNB
HGNC
Name
filamin B
HGNC
NCBI Gene ID
2317
NCBI Gene
HGNC ID
HGNC:3755
HGNC
Ensembl
ENSG00000136068
NCBI Gene
Aliases
ABP-278, ABP-280, FH1, FLN-B, FLN1L, LRS1, TABP, TAP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75369Filamin-B2,60223Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446353O75369Espacenet
EP 4650780 A22025-11-193669O75369Espacenet
EP 4641201 A22025-10-293268O75369Espacenet
EP 4641202 A22025-10-29192O75369Espacenet
JP 2025517969 A2025-06-123268O75369Espacenet
JP 2025517970 A2025-06-123669O75369Espacenet
JP 2025032204 A2025-03-1128497O75369Espacenet
WO 2025032112 A12025-02-132O75369Espacenet
KR 1020250017231 A2025-02-04192O75369Espacenet
EP 4461818 A22024-11-1328497O75369Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,659

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFLNB papersNewest fiscal year
P30CA008748Cancer Center Support Grant132025
R01AI044115Influences of HLA Class I Polymorphisms on immune responses132025
P30CA016672Cancer Center Support Grant102025
T32CA009476Cancer Biology Training Program92025
P30CA036727Buffett Cancer Center Support Grant82025
P30CA023108Cancer Center Support Grant72025
P30CA076292Moffitt Cancer Center Support Grant62025
ZIABC010984Adoptive Cell Transfer Immunotherapy of Cancer62025
P01CA018029Adult Leukemia Research Center52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025

1 to 10 of 2,659Source NIH's project files

See all 2,659 nih grants

Papers3,759

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Filamin B (FLNB)-Related Spondylocarpotarsal Synostosis Syndrome: Systematic Literature Review and Novel Case Report.Genes (Basel)202642792948PubTator, text miningPubMed
Multi-omics screening and functional validation identify SLC5A6 as a candidate disulfidptosis-related gene and prognostic biomarker in hepatocellular carcinoma.Front Oncol202642666251PubTator, text miningPubMed
HIRA loss is frequent but not universal in human fumarate hydratase-deficient renal cell carcinoma and defines divergent oncogenic programs.Biomark Res202642638137PubTator, text miningPubMed
Clinical value of serum osteocalcin (N-MID) combined with thyroid transcription factor-1 for predicting bone metastasis of lung cancer.Am J Cancer Res202642597206PubTator, text miningPubMed
LRS1 phosphorylated in response to blue light regulates stomatal opening.J Plant Res202642573725PubTator, text miningPubMed
A placental DNA methylation score associated with early-onset preeclampsia and maternal vascular malperfusion pathology.Front Epigenet Epigenom202642559650PubTator, text miningPubMed
ATP-driven conformational dynamics reveal hidden intermediates in a heterodimeric ABC transporter.Elife202642535643PubTator, text miningPubMed
High-resolution mapping of chromatin conformation in HBeAg-treated macrophage provides insights into pathogenesis of HBV-related liver diseases.Front Immunol202642534908PubTator, text miningPubMed
Genotype-phenotype correlations in children with short stature: results of targeted next-generation sequencing.J Pediatr Endocrinol Metab202642446396PubTator, text miningPubMed
Development and Validation of a Six-Gene Signature of Myeloid Antigen Presentation Dysfunction Based on Single-Cell and Multi-Cohort Transcriptomics for Predicting Prognosis and Recurrence of Hepatocellular Carcinoma.
Cancer Inform202642404398PubTator, text miningPubMed

1 to 10 of 3,759

See all 3,759 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2317

GET https://conductscience.org/api/genes/v1/2317/patents?page=2