Gene · 23175
LPIN1: lipin 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LPIN1: lipin 1. Genes, record 23175. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23175
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14693 | Phosphatidate phosphatase LPIN1 | 890 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 51840 | Q14693 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1602 | Q14693 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1210 | Q14693 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1210 | Q14693 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1602 | Q14693 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47007 | Q14693 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 149978 | Q14693 | Espacenet |
| KR 1020210128370 A | 2021-10-26 | 22 | Q14693 | Espacenet |
| US 11020429 B2 | 2021-06-01 | 24 | Q14693 | Espacenet |
| US 10881746 B2 | 2021-01-05 | 1 | Q14693 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,295
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LPIN1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK056341 | Washington University Nutrition Obesity Research Center | 20 | 2025 |
| P30DK020579 | Diabetes Research Center | 10 | 2025 |
| T32HG002536 | Training Grant in Genomic Analysis and Interpretation | 9 | 2025 |
| P30DK052574 | Host-environment interactions in the pathophysiology of digestive disease | 7 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| R35GM136128 | Regulation and Role of Phosphatidate Phosphatase in Lipid Metabolism | 5 | 2025 |
| U01DK061734 | Clinical Research on Nonalcoholic Fatty Liver Disease | 5 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 4 | 2025 |
| P50AA024333 | Alcohol and tissue injury, from mechanisms to treatments | 4 | 2025 |
1 to 10 of 1,295Source NIH's project files
See all 1,295 nih grantsPapers1,577
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Large-Scale Cellular Phosphoproteomic Analysis Reveals a Putative Role for LPIN1 S162 in Metabolic Signaling. | OMICS | 2026 | 42657976 | PubTator, text mining | PubMed |
| Circadian Regulation of Glucose Metabolism: Implications for Pathogenesis and Chronotherapy of Type 2 Diabetes. | Diabetology (Basel) | 2026 | 42583078 | PubTator, text mining | PubMed |
| Early identification of LPIN1 variant in a child with severe myoglobinuria and a history of sibling deaths. | CEN Case Rep | 2026 | 42545443 | PubTator, text mining | PubMed |
| Unveiling the dynamic transcriptomic changes in and replicative senescence balance of hUC-MSCs: A comparative study of serum-containing versus serum-free culture supplements. | Tissue Cell | 2026 | 42537251 | PubTator, text mining | PubMed |
| Role of Lipin-1 in Macrophage-Mediated Atherosclerosis: Is It Atherogenic or Atheroprotective? | J Am Heart Assoc | 2026 | 42535557 | PubTator, text mining | PubMed |
| Copper induces depressive-like behavior through neuronal lipid accumulation mediated by Lipin-1. | Neurotoxicology | 2026 | 42442639 | PubTator, text mining | PubMed |
| Fatty acid metabolism and lipid channeling in macrophages: mechanisms of inflammation, resolution, and lipotoxicity. | Front Immunol | 2026 | 42367816 | PubTator, text mining | PubMed |
| When Dark Urine Is Not Nephritis: A Life-Threatening Case of Lipin-1 Deficiency in Infancy. | Cureus | 2026 | 42220764 | PubTator, text mining | PubMed |
| Ursocholic acid ameliorates hepatic steatosis via direct AMPK activation in preclinical models of MASLD. | Eur J Pharmacol | 2026 | 42128193 | PubTator, text mining | PubMed |
| Dynamic Role of Omega-3/Omega-6 Polyunsaturated Fatty Acid Ratio in Modulation of Adipogenicity, Lipid Metabolites, and Adipokines Associated with Platelet Hyperactivity. | Metabolites | 2026 | 42042916 | PubTator, text mining | PubMed |
1 to 10 of 1,577
See all 1,577 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23175
GET https://conductscience.org/api/genes/v1/23175/patents?page=2