Gene · 2318
FLNC: filamin C
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FLNC: filamin C. Genes, record 2318. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2318
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14315 | Filamin-C | 2,725 | 14 | Ensembl, GeneID, HGNC |
Source UniProt
Patents34
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 46361 | Q14315 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5708 | Q14315 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 821 | Q14315 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5362 | Q14315 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 821 | Q14315 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5362 | Q14315 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5708 | Q14315 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 368 | Q14315 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 190 | Q14315 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 32170 | Q14315 | Espacenet |
1 to 10 of 34
See all 34 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,170
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FLNC papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 5 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 5 | 2025 |
| R01AR068797 | Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| P50HD027802 | Differential Diagnosis in Learning Disabilities | 4 | 2025 |
| R01AG031867 | Protein aggregation in inclusion body and myofibrillar myopathies | 4 | 2025 |
1 to 10 of 2,170Source NIH's project files
See all 2,170 nih grantsPapers3,704
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cutaneous ultrastructure reveals potential biomarkers of ventricular arrhythmias in inflammatory cardiomyopathy. | Ultrastruct Pathol | 2026 | 42827311 | PubTator, text mining | PubMed |
| Cardiologist-Delivered Genetic Testing in 482 Patients With Cardiomyopathy: The Infrastructure Needed for Mainstream Testing at Scale. | Circ Genom Precis Med | 2026 | 42825316 | PubTator, text mining | PubMed |
| FLNC-Related Cardiomyopathies in an Admixed Population: Expanding the Genotype-Phenotype Spectrum and Clinical Correlates. | Circ Genom Precis Med | 2026 | 42825315 | PubTator, text mining | PubMed |
| The Multifaceted Role of the FLNC Gene in Hereditary Cardiomyopathies and Prognosis. | Genes (Basel) | 2026 | 42793030 | PubTator, text mining | PubMed |
| Endothelial Filamin C Alleviates Atherosclerosis via PINK1/Parkin-Dependent Mitophagy and mtDNA-cGAS-STING Inflammation Suppression. | J Cardiovasc Dev Dis | 2026 | 42783035 | PubTator, text mining | PubMed |
| SEME enables programmable transcript reconstruction through synthetic microexon incorporation. | bioRxiv | 2026 | 42779617 | PubTator, text mining | PubMed |
| Identification of novel and known variants in GAA, MYH6, NEXN, ATA3A, RHBDF1, and ACTA1 genes in coronary artery disease patients by Whole-exome sequencing. | Front Cardiovasc Med | 2026 | 42760933 | PubTator, text mining | PubMed |
| Extraction-dependent changes in immunoglobulin E binding profiles of processed lesser mealworm (Alphitobius diaperinus) proteins. | J Sci Food Agric | 2026 | 42745438 | PubTator, text mining | PubMed |
| Childhood-Onset Filamin c Related Cardiomyopathy: Genotype-Phenotype Correlation and Outcome. | Clin Genet | 2026 | 42733184 | PubTator, text mining | PubMed |
| Prevalence of Pathogenic Genetic Variants Across Heart Failure Etiologies in an Admixed Population. | JACC Adv | 2026 | 42658137 | PubTator, text mining | PubMed |
1 to 10 of 3,704
See all 3,704 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2318
GET https://conductscience.org/api/genes/v1/2318/patents?page=2