Gene · 23186
RCOR1: REST corepressor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RCOR1: REST corepressor 1. Genes, record 23186. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23186
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UKL0 | REST corepressor 1 | 485 | 103 | Ensembl, GeneID, HGNC |
Source UniProt
Patents46
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4828973 A2 | 2026-10-28 | 56 | Q9UKL0 | Espacenet |
| EP 4805378 A1 | 2026-09-16 | 567 | Q9UKL0 | Espacenet |
| JP 2026523341 A | 2026-07-14 | 1026 | Q9UKL0 | Espacenet |
| EP 4771137 A1 | 2026-07-08 | 564 | Q9UKL0 | Espacenet |
| EP 4771157 A1 | 2026-07-08 | 564 | Q9UKL0 | Espacenet |
| US 12649003 B2 | 2026-06-09 | 1026 | Q9UKL0 | Espacenet |
| JP 2026510339 A | 2026-04-02 | 564 | Q9UKL0 | Espacenet |
| EP 4713451 A2 | 2026-03-25 | 564 | Q9UKL0 | Espacenet |
| EP 4713452 A2 | 2026-03-25 | 564 | Q9UKL0 | Espacenet |
| US 12558437 B2 | 2026-02-24 | 1026 | Q9UKL0 | Espacenet |
1 to 10 of 46
See all 46 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,838
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RCOR1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 7 | 2025 |
| R35GM149229 | Chemical Approaches to Understanding Reversible Lysine Modifications | 7 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 5 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 5 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 5 | 2025 |
| P30AI036219 | Rustbelt Center for AIDS Research (Case/UHC-Pitt CFAR) | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 4 | 2025 |
1 to 10 of 1,838Source NIH's project files
See all 1,838 nih grantsPapers2,104
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| REST in the Central Nervous System: Context-Dependent Regulation of Neuronal Homeostasis and Disease. | Int J Dev Neurosci | 2026 | 42827376 | PubTator, text mining | PubMed |
| Multicomplex Integrative Structural Modeling of a Human Histone Deacetylase Interactome. | Mol Cell Proteomics | 2026 | 42680104 | PubTator, text mining | PubMed |
| Structure-Guided Optimization of a Molecular Glue Targeting the KBTBD4-HDAC1/2 Complex. | ChemMedChem | 2026 | 42642754 | PubTator, text mining | PubMed |
| Cancer-associated KBTBD4 mutations induce differentiation defects and confer a unique therapeutic vulnerability. | Cancer Gene Ther | 2026 | 42576054 | PubTator, text mining | PubMed |
| The CoREST complex inhibitor, corin, decreases tumor growth, increases cellular differentiation and extends lifespan in ATRT xenograft models. | Neuro Oncol | 2026 | 42479134 | PubTator, text mining | PubMed |
| DNA Methylation and Proteomic Profiling of Postmortem Brain Tissue Reveals Epigenetic Dysregulation and Neuroinflammatory in Fragile X-associated Tremor/Ataxia Syndrome (FXTAS). | bioRxiv | 2026 | 42465430 | PubTator, text mining | PubMed |
| Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex. | Nucleic Acids Res | 2026 | 42376816 | PubTator, text mining | PubMed |
| The Reconstitution of the Macrophage Niche Reveals Dynamic Transcriptional and Renal Macrophage-Epithelial Communication Networks. | Cells | 2026 | 42346129 | PubTator, text mining | PubMed |
| Reduced FBXO22 skews human trophoblast fate equilibrium toward syncytialization via polyubiquitinating the CoREST complex. | Nucleic Acids Res | 2026 | 42240618 | PubTator, text mining | PubMed |
| NANOG Proximity Proteomics Maps Neighborhood Hubs Linked to Mesenchymal Stem Cell Stemness and Chromatin Control. | Biomolecules | 2026 | 42072652 | PubTator, text mining | PubMed |
1 to 10 of 2,104
See all 2,104 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23186
GET https://conductscience.org/api/genes/v1/23186/patents?page=2