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Gene · 23210

JMJD6: jumonji domain containing 6, arginine demethylase and lysine hydroxylase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. JMJD6: jumonji domain containing 6, arginine demethylase and lysine hydroxylase. Genes, record 23210. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23210

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Gene

Symbol
JMJD6
HGNC
Name
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
HGNC
NCBI Gene ID
23210
NCBI Gene
HGNC ID
HGNC:19355
HGNC
Ensembl
ENSG00000070495
NCBI Gene
Aliases
KIAA0585, PSR, PTDSR, PTDSR1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6NYC1Bifunctional arginine demethylase and lysyl-hydroxylase JMJD64036Ensembl, GeneID, HGNC

Source UniProt

Patents11

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450483Q6NYC1Espacenet
JP 2024507735 A2024-02-21191Q6NYC1Espacenet
JP 2024502906 A2024-01-234Q6NYC1Espacenet
US 11446398 B22022-09-2042340Q6NYC1Espacenet
JP 2022524081 A2022-04-27145311Q6NYC1Espacenet
JP 2019054813 A2019-04-11230918Q6NYC1Espacenet
EP 3262076 A12018-01-0350Q6NYC1Espacenet
JP 2017121241 A2017-07-13230918Q6NYC1Espacenet
JP 2015516143 A2015-06-08230918Q6NYC1Espacenet
EP 2403963 A12012-01-116Q6NYC1Espacenet

1 to 10 of 11

See all 11 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,164

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleJMJD6 papersNewest fiscal year
P30CA016672Cancer Center Support Grant72025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant52025
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair52025
R01DK039773Mechanisms of Ischemic Kidney Injury and Repair42025
R01GM062248Computational Enzymology to Study Diverse Catalytic Strategies of RNA42025
T32AI007533Training in Molecular Virology, Viral Pathogenesis and Viral Vectors42025
P30CA008748Cancer Center Support Grant32025
P30CA045508CSHL Cancer Center Support Grant32025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
T32AI007405Training Program in Immunology32025

1 to 10 of 1,164Source NIH's project files

See all 1,164 nih grants

Papers1,476

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Overexpression of JMJD6 Drives Immune Evasion via the BRD4-IRF1-PD-L1 Axis and Promotes Malignancy in Gastric Cancer].Gan To Kagaku Ryoho202642750620PubTator, text miningPubMed
Kidney Injury Molecule-1: A Biomarker, Signalling Mediator, and Therapeutic Target.Semin Nephrol202642736091PubTator, text miningPubMed
Dual roles of JMJD6 in oncogenesis and immune evasion: molecular mechanisms and therapeutic prospects.Biochem Biophys Res Commun202642361741PubTator, text miningPubMed
Androgen receptor splice variant 7 (AR-V7) in castration-resistant prostate cancer: Molecular mechanisms and therapeutic strategies.Urol Oncol202642115122PubTator, text miningPubMed
JMJD6-mediated epigenetic silencing of innate immunity promotes pseudorabies virus replication.J Virol202642053297PubTator, text miningPubMed
Molecular recognition and induced dimerization of hnRNP A2/B1 truncations by G-quadruplex single strand DNA.Sci Rep202641888191PubTator, text miningPubMed
The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets.Mol Biomed202641857315PubTator, text miningPubMed
Pan-cancer analysis identifies JMJD6 as an oncogene and prognostic biomarker.Discov Oncol202641849021PubTator, text miningPubMed
Demonstration of the Role of Both a Ttr and a Psr Homologue Enzymes in the Respiration of Tetrathionate by an Environmental Bacterium Shewanella sp. ANA-3.Environ Microbiol202641761654PubTator, text miningPubMed
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.Pharmaceutics202641755020PubTator, text miningPubMed

1 to 10 of 1,476

See all 1,476 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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