Gene · 2328
FMO3: flavin containing dimethylaniline monoxygenase 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FMO3: flavin containing dimethylaniline monoxygenase 3. Genes, record 2328. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2328
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P31513 | Flavin-containing monooxygenase 3 | 532 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 46408 | P31513 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 46409 | P31513 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8288 | P31513 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8474 | P31513 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5478 | P31513 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1595 | P31513 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6405 | P31513 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1595 | P31513 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6405 | P31513 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8474 | P31513 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants834
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FMO3 papers | Newest fiscal year |
|---|---|---|---|
| T32ES007015 | Molecular & Environmental Toxicology Predoctoral Training Program | 9 | 2025 |
| P50AA024333 | Alcohol and tissue injury, from mechanisms to treatments | 8 | 2025 |
| P30DK056350 | Nutrition Obesity Research Center (NORC) | 4 | 2025 |
| R01HD081299 | Ontogeny of drug transport | 4 | 2025 |
| R01HL034594 | RISK FACTORS FOR CVD IN WOMEN | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA077598 | Cancer Center Support Grant | 3 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 3 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 3 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 3 | 2025 |
1 to 10 of 834Source NIH's project files
See all 834 nih grantsPapers1,499
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| [Pharmacokinetics and Metabolic Activations of Drugs in Pharmacology and Toxicology]. | Yakugaku Zasshi | 2026 | 42816351 | PubTator, text mining | PubMed |
| Toxicokinetics and analytical toxicology of four N, N-dimethyltryptamine derivatives studied in human in vitro systems and in vivo by means of zebrafish embryos. | Arch Toxicol | 2026 | 42768110 | PubTator, text mining | PubMed |
| Decoding the Link: Exploring FMO3 Gene Variations as a Key to Understanding Type Two Diabetes Through Bioinformatics and Case-Control Analyses. | Indian J Clin Biochem | 2026 | 42712703 | PubTator, text mining | PubMed |
| [Metabolic Activations and Pharmacokinetics of Drugs Using Data-driven Modeling]. | Yakugaku Zasshi | 2026 | 42686527 | PubTator, text mining | PubMed |
| β-cell FMO3-produced TMAO prevents NF-κB-mediated senescence and inflammation in ageing and diabetic conditions. | Nat Commun | 2026 | 42649194 | PubTator, text mining | PubMed |
| Gut microbiota-derived TMA/TMAO and IRAK4 signaling in type 2 diabetes: Current evidence, knowledge gaps and future therapeutic opportunities. | Int Immunopharmacol | 2026 | 42594838 | PubTator, text mining | PubMed |
| Hepatic FMO3 Downregulation Contributes to the Metabolic Benefits of Vertical Sleeve Gastrectomy. | Obesity (Silver Spring) | 2026 | 42555205 | PubTator, text mining | PubMed |
| Divergence between circulating trimethylamine and trimethylamine-N-oxide associated with common flavin-containing monooxygenase 3 variation. | iScience | 2026 | 42519056 | PubTator, text mining | PubMed |
The Relationship Between Adherence to the Mediterranean Diet, Oxidative Stress, Trimethylamine N-Oxide, and Inflammatory Markers in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease. | Nutrients | 2026 | 42514300 | PubTator, text mining | PubMed |
| Trimethylamine N-Oxide and Impaired Spermatogenesis in the Gut-Testis Axis: A Focused Review of Current Evidence. | Biology (Basel) | 2026 | 42450625 | PubTator, text mining | PubMed |
1 to 10 of 1,499
See all 1,499 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2328
GET https://conductscience.org/api/genes/v1/2328/patents?page=2