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Gene · 2328

FMO3: flavin containing dimethylaniline monoxygenase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FMO3: flavin containing dimethylaniline monoxygenase 3. Genes, record 2328. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2328

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Gene

Symbol
FMO3
HGNC
Name
flavin containing dimethylaniline monoxygenase 3
HGNC
NCBI Gene ID
2328
NCBI Gene
HGNC ID
HGNC:3771
HGNC
Ensembl
ENSG00000007933
NCBI Gene
Aliases
FMOII, TMAU, dJ127D3.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P31513Flavin-containing monooxygenase 35320Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446408P31513Espacenet
JP 2026004568 A2026-01-1446409P31513Espacenet
EP 4650780 A22025-11-198288P31513Espacenet
EP 4641201 A22025-10-298474P31513Espacenet
JP 2025147176 A2025-10-065478P31513Espacenet
JP 2025529142 A2025-09-041595P31513Espacenet
JP 2025529142 A2025-09-046405P31513Espacenet
US 12371689 B22025-07-291595P31513Espacenet
US 12371689 B22025-07-296405P31513Espacenet
JP 2025517969 A2025-06-128474P31513Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants834

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFMO3 papersNewest fiscal year
T32ES007015Molecular & Environmental Toxicology Predoctoral Training Program92025
P50AA024333Alcohol and tissue injury, from mechanisms to treatments82025
P30DK056350Nutrition Obesity Research Center (NORC)42025
R01HD081299Ontogeny of drug transport42025
R01HL034594RISK FACTORS FOR CVD IN WOMEN42025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA077598Cancer Center Support Grant32025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)32025
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment32025
P30ES007048Environmental Exposures, Host Factors and Human Disease32025

1 to 10 of 834Source NIH's project files

See all 834 nih grants

Papers1,499

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Pharmacokinetics and Metabolic Activations of Drugs in Pharmacology and Toxicology].Yakugaku Zasshi202642816351PubTator, text miningPubMed
Toxicokinetics and analytical toxicology of four N, N-dimethyltryptamine derivatives studied in human in vitro systems and in vivo by means of zebrafish embryos.Arch Toxicol202642768110PubTator, text miningPubMed
Decoding the Link: Exploring FMO3 Gene Variations as a Key to Understanding Type Two Diabetes Through Bioinformatics and Case-Control Analyses.Indian J Clin Biochem202642712703PubTator, text miningPubMed
[Metabolic Activations and Pharmacokinetics of Drugs Using Data-driven Modeling].Yakugaku Zasshi202642686527PubTator, text miningPubMed
β-cell FMO3-produced TMAO prevents NF-κB-mediated senescence and inflammation in ageing and diabetic conditions.Nat Commun202642649194PubTator, text miningPubMed
Gut microbiota-derived TMA/TMAO and IRAK4 signaling in type 2 diabetes: Current evidence, knowledge gaps and future therapeutic opportunities.Int Immunopharmacol202642594838PubTator, text miningPubMed
Hepatic FMO3 Downregulation Contributes to the Metabolic Benefits of Vertical Sleeve Gastrectomy.Obesity (Silver Spring)202642555205PubTator, text miningPubMed
Divergence between circulating trimethylamine and trimethylamine-N-oxide associated with common flavin-containing monooxygenase 3 variation.iScience202642519056PubTator, text miningPubMed
The Relationship Between Adherence to the Mediterranean Diet, Oxidative Stress, Trimethylamine N-Oxide, and Inflammatory Markers in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease.
Nutrients202642514300PubTator, text miningPubMed
Trimethylamine N-Oxide and Impaired Spermatogenesis in the Gut-Testis Axis: A Focused Review of Current Evidence.Biology (Basel)202642450625PubTator, text miningPubMed

1 to 10 of 1,499

See all 1,499 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2328

GET https://conductscience.org/api/genes/v1/2328/patents?page=2