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FN1: fibronectin 1

1 protein, 56 patents, 7 drugs, 26 trials, 28,633 NIH grants and 88,228 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFN1HGNC
Namefibronectin 1HGNC
NCBI Gene ID2335NCBI Gene
HGNC IDHGNC:3778HGNC
EnsemblENSG00000115414NCBI Gene
AliasesCIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, SMDCF, lnc-ABCA12-8NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P02751Fibronectin2,47765Ensembl, GeneID, HGNCUniProt

Patents 56

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026507050 A2026-02-275P02751Espacenet
JP 2026504906 A2026-02-1048P02751Espacenet
EP 4650780 A22025-11-197097P02751Espacenet
EP 4640849 A22025-10-291043P02751Espacenet
EP 4641201 A22025-10-297001P02751Espacenet
KR 1020250152088 A2025-10-225P02751Espacenet
JP 2025147176 A2025-10-065490P02751Espacenet
JP 2025140989 A2025-09-291P02751Espacenet
EP 4615516 A12025-09-175P02751Espacenet
KR 1020250136390 A2025-09-1648P02751Espacenet

Drugs 7

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AS-1409CHEMBL2109413Fibronectin binding agentBINDING AGENTChEMBL
L19IL2CHEMBL2109608Fibronectin binding agentBINDING AGENTChEMBL
L19SIP 131ICHEMBL2109412Fibronectin otherOTHERChEMBL
L19TNFACHEMBL2109589Fibronectin binding agentBINDING AGENTChEMBL
MU-BC-1CHEMBL2109529Fibronectin binding agentBINDING AGENTChEMBL
OCRIPLASMINCHEMBL2095222Fibronectin proteolytic enzymePROTEOLYTIC ENZYMEChEMBL
RADRETUMABCHEMBL1743060Fibronectin binding agentBINDING AGENTChEMBL

Trials 26

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07566897L19IL2PHASE1ClinicalTrials.gov
NCT07228442L19IL2PHASE2ClinicalTrials.gov
NCT07227350L19IL2PHASE2ClinicalTrials.gov
NCT06284590L19IL2PHASE2ClinicalTrials.gov
NCT05329792L19IL2PHASE2ClinicalTrials.gov
NCT04362722L19IL2PHASE2ClinicalTrials.gov
NCT02957019L19IL2PHASE1/PHASE2ClinicalTrials.gov
NCT02938299L19IL2PHASE3ClinicalTrials.gov
NCT02747030OCRIPLASMINPHASE1ClinicalTrials.gov
NCT02735850L19IL2PHASE2ClinicalTrials.gov

NIH grants 28633

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2542,025NIH's project files
P30CA008748Cancer Center Support Grant1742,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)892,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support872,025NIH's project files
P30EY016665Core Grant for Vision Research602,025NIH's project files
P30CA068485Cancer Center Support Grant562,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center552,025NIH's project files
P30CA016058Cancer Center Support Grant522,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award522,025NIH's project files
P30CA014051Cancer Center Support (Core) Grant512,025NIH's project files

Papers 88228

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827249PubTator, text miningPubMed
42821141PubTator, text miningPubMed
42816685PubTator, text miningPubMed
42815885PubTator, text miningPubMed
42815047PubTator, text miningPubMed
42812615PubTator, text miningPubMed
42808650PubTator, text miningPubMed
42805572PubTator, text miningPubMed
42805285PubTator, text miningPubMed
42802716PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license