Gene · 23373
CRTC1: CREB regulated transcription coactivator 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CRTC1: CREB regulated transcription coactivator 1. Genes, record 23373. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23373
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q6UUV9 | CREB-regulated transcription coactivator 1 | 634 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12553882 B2 | 2026-02-17 | 3 | Q6UUV9 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 42361 | Q6UUV9 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5489 | Q6UUV9 | Espacenet |
| JP 2025170454 A | 2025-11-19 | 28 | Q6UUV9 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5102 | Q6UUV9 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5102 | Q6UUV9 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5489 | Q6UUV9 | Espacenet |
| WO 2024071437 A | 2024-04-04 | 28 | Q6UUV9 | Espacenet |
| KR 1020240011120 A | 2024-01-25 | 618 | Q6UUV9 | Espacenet |
| JP 2024501383 A | 2024-01-11 | 642 | Q6UUV9 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,107
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CRTC1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 39 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 31 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 16 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 15 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 13 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 11 | 2025 |
| R01CA137008 | Non-genomic resistance mechanisms in EGFR-mutant lung cancer | 9 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 7 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 7 | 2025 |
| P40OD018537 | Bloomington Drosophila Stock Center at Indiana University | 7 | 2025 |
1 to 10 of 2,107Source NIH's project files
See all 2,107 nih grantsPapers2,891
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Case Report: Treatment of an unresectable mucoepidermoid carcinoma with osimertinib. | Front Oncol | 2026 | 42798538 | PubTator, text mining | PubMed |
| CRTC, not phosphorylated CREB1, drives cAMP-induced transcription across diverse cell types. | bioRxiv | 2026 | 42619677 | PubTator, text mining | PubMed |
| Bilateral Multifocal Nodular Oncocytic Hyperplasia of the Parotid Gland Mimicking Warthin Tumor and Acinic Cell Carcinoma: A Case Report and Literature Review. | J Clin Exp Dent | 2026 | 42482881 | PubTator, text mining | PubMed |
| Pharmacogenomics of antipsychotic-induced weight gain: A systematic review. | Schizophr Res | 2026 | 42480244 | PubTator, text mining | PubMed |
| Design Principles and Architecture of Cellular Nutrient Signaling. | Annu Rev Genet | 2026 | 42475414 | PubTator, text mining | PubMed |
| Duloxetine ameliorates chronic stress-induced depressive behaviors by normalizing hippocampal SIK2-CRTC1 signaling. | Front Pharmacol | 2026 | 42465993 | PubTator, text mining | PubMed |
| Genomic signature of repeated transitions to diurnality in spiders. | Mol Biol Evol | 2026 | 42389982 | PubTator, text mining | PubMed |
| Mechanisms of weight gain associated with valproic acid: a scoping review. | Eur Arch Psychiatry Clin Neurosci | 2026 | 42334569 | PubTator, text mining | PubMed |
| Encouraging a move toward precision geromedicine. | Geromedicine | 2026 | 42266612 | PubTator, text mining | PubMed |
| Kog1 Represses Lipid Accumulation in Mucor circinelloides: A Transcriptomic Analysis Across Nitrogen Conditions. | J Fungi (Basel) | 2026 | 42042360 | PubTator, text mining | PubMed |
1 to 10 of 2,891
See all 2,891 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23373
GET https://conductscience.org/api/genes/v1/23373/patents