ConductScience.org, home

Gene · 23373

CRTC1: CREB regulated transcription coactivator 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. CRTC1: CREB regulated transcription coactivator 1. Genes, record 23373. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23373

On this page

Gene

Symbol
CRTC1
HGNC
Name
CREB regulated transcription coactivator 1
HGNC
NCBI Gene ID
23373
NCBI Gene
HGNC ID
HGNC:16062
HGNC
Ensembl
ENSG00000105662
NCBI Gene
Aliases
FLJ14027, KIAA0616, MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6UUV9CREB-regulated transcription coactivator 16343Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12553882 B22026-02-173Q6UUV9Espacenet
JP 2026004568 A2026-01-1442361Q6UUV9Espacenet
EP 4650780 A22025-11-195489Q6UUV9Espacenet
JP 2025170454 A2025-11-1928Q6UUV9Espacenet
EP 4641201 A22025-10-295102Q6UUV9Espacenet
JP 2025517969 A2025-06-125102Q6UUV9Espacenet
JP 2025517970 A2025-06-125489Q6UUV9Espacenet
WO 2024071437 A2024-04-0428Q6UUV9Espacenet
KR 1020240011120 A2024-01-25618Q6UUV9Espacenet
JP 2024501383 A2024-01-11642Q6UUV9Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,107

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCRTC1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant392025
P30CA016672Cancer Center Support Grant312025
P30CA068485Cancer Center Support Grant162025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes152025
P40OD010440Caenorhabditis Genetics Center132025
P30CA006973Regional Oncology Research Center112025
R01CA137008Non-genomic resistance mechanisms in EGFR-mutant lung cancer92025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center72025
P30DK020572Michigan Diabetes Research Center (MDRC)72025
P40OD018537Bloomington Drosophila Stock Center at Indiana University72025

1 to 10 of 2,107Source NIH's project files

See all 2,107 nih grants

Papers2,891

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Case Report: Treatment of an unresectable mucoepidermoid carcinoma with osimertinib.Front Oncol202642798538PubTator, text miningPubMed
CRTC, not phosphorylated CREB1, drives cAMP-induced transcription across diverse cell types.bioRxiv202642619677PubTator, text miningPubMed
Bilateral Multifocal Nodular Oncocytic Hyperplasia of the Parotid Gland Mimicking Warthin Tumor and Acinic Cell Carcinoma: A Case Report and Literature Review.J Clin Exp Dent202642482881PubTator, text miningPubMed
Pharmacogenomics of antipsychotic-induced weight gain: A systematic review.Schizophr Res202642480244PubTator, text miningPubMed
Design Principles and Architecture of Cellular Nutrient Signaling.Annu Rev Genet202642475414PubTator, text miningPubMed
Duloxetine ameliorates chronic stress-induced depressive behaviors by normalizing hippocampal SIK2-CRTC1 signaling.Front Pharmacol202642465993PubTator, text miningPubMed
Genomic signature of repeated transitions to diurnality in spiders.Mol Biol Evol202642389982PubTator, text miningPubMed
Mechanisms of weight gain associated with valproic acid: a scoping review.Eur Arch Psychiatry Clin Neurosci202642334569PubTator, text miningPubMed
Encouraging a move toward precision geromedicine.Geromedicine202642266612PubTator, text miningPubMed
Kog1 Represses Lipid Accumulation in Mucor circinelloides: A Transcriptomic Analysis Across Nitrogen Conditions.J Fungi (Basel)202642042360PubTator, text miningPubMed

1 to 10 of 2,891

See all 2,891 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/23373

GET https://conductscience.org/api/genes/v1/23373/patents