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Gene · 23400

ATP13A2: ATPase cation transporting 13A2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATP13A2: ATPase cation transporting 13A2. Genes, record 23400. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23400

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Gene

Symbol
ATP13A2
HGNC
Name
ATPase cation transporting 13A2
HGNC
NCBI Gene ID
23400
NCBI Gene
HGNC ID
HGNC:30213
HGNC
Ensembl
ENSG00000159363
NCBI Gene
Aliases
CLN12, HSA9947, KRPPD, PARK9, SPG78
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NQ11Polyamine-transporting ATPase 13A21,18025Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21256Q9NQ11Espacenet
JP 2026004568 A2026-01-1438152Q9NQ11Espacenet
JP 2025529142 A2025-09-04493Q9NQ11Espacenet
US 12371689 B22025-07-29493Q9NQ11Espacenet
JP 2025062601 A2025-04-1484Q9NQ11Espacenet
JP 2025062604 A2025-04-147182Q9NQ11Espacenet
JP 2023123507 A2023-09-05247Q9NQ11Espacenet
JP 2023521663 A2023-05-25255Q9NQ11Espacenet
US 11446398 B22022-09-207182Q9NQ11Espacenet
JP 2022524081 A2022-04-27110153Q9NQ11Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants974

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATP13A2 papersNewest fiscal year
R01ES010563Mechanisms of Manganese Neurotoxicity272025
R01ES007331Mechanisms of Methylmercury Induced Neuronal Toxicity122025
P40OD010440Caenorhabditis Genetics Center82025
R01NS060123Neuronal Autophagy: a Cell-Autonomous Protection Mechanism62025
ZIAHG200336Genetic and clinical studies of Gaucher disease and other lysosomal disorders62025
R01NS072248Genome Studies in Hereditary Spastic Paraplegia- Beyond the Exome52025
R01NS092823The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function52025
T32ES007028Training Program in Environmental Toxicology52025
ZIANS003154Genetic characterization of atypical parkinsonism52025
R01ES019222Metal mixtures, exposure windows, and neurodevelopmental trajectories from adolescence to adulthood32025

1 to 10 of 974Source NIH's project files

See all 974 nih grants

Papers1,821

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Retraction Notice to: Lysosomal polyamine storage upon ATP13A2 loss impairs β-glucocerebrosidase via altered lysosomal pH and electrostatic hydrolase-lipid interactions.Cell Rep202642804365PubTator, text miningPubMed
Genetic architecture and molecular pathogenesis of Parkinson's disease: emerging mechanisms and therapeutic targets.Metab Brain Dis202642803978PubTator, text miningPubMed
Dysregulated polyamine metabolism in neurological disorders: molecular mechanisms and therapeutic opportunities.Mol Biol Rep202642771220PubTator, text miningPubMed
Defective ATP13A2-ITCH-ALIX signaling impairs intraluminal vesicle biogenesis and increases neuronal vulnerability.Cell Signal202642762936PubTator, text miningPubMed
Exploring cerebral small vessel disease signatures in familial Parkinson's disease.Sci Rep202642706363PubTator, text miningPubMed
Polyamine Metabolism in Brain Health and Disease.Neuropharmacol Ther202642631064PubTator, text miningPubMed
Polyamines buffer labile iron to suppress ferroptosis.Cell202642600612PubTator, text miningPubMed
ATP13A2 Promotes Endothelial Angiogenic Phenotypes and Is Associated With Poor Prognosis in Liver Hepatocellular Carcinoma.Mol Carcinog202642574576PubTator, text miningPubMed
Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications.Lancet Neurol202642456684PubTator, text miningPubMed
Correction to "Structural Dynamics and Catalytic Mechanism of ATP13A2 (PARK9) from Simulations".J Phys Chem B202642439853PubTator, text miningPubMed

1 to 10 of 1,821

See all 1,821 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/23400

GET https://conductscience.org/api/genes/v1/23400/patents?page=2