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SF3B1: splicing factor 3b subunit 1

1 protein, 55 patents, 0 drugs, 0 trials, 2,883 NIH grants and 6,124 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSF3B1HGNC
Namesplicing factor 3b subunit 1HGNC
NCBI Gene ID23451NCBI Gene
HGNC IDHGNC:10768HGNC
EnsemblENSG00000115524NCBI Gene
AliasesHsh155, MDS, PRP10, PRPF10, Prp10, SAP155, SF3b155NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O75533Splicing factor 3B subunit 11,30474Ensembl, GeneID, HGNCUniProt

Patents 55

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465333O75533Espacenet
EP 4650780 A22025-11-196170O75533Espacenet
EP 4641201 A22025-10-295918O75533Espacenet
EP 4623996 A22025-10-011O75533Espacenet
JP 2025529142 A2025-09-043920O75533Espacenet
WO 2025178991 A12025-08-2887O75533Espacenet
US 12371689 B22025-07-293920O75533Espacenet
JP 2025517969 A2025-06-125918O75533Espacenet
JP 2025517970 A2025-06-126170O75533Espacenet
US 12275766 B22025-04-15108O75533Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2883

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1422,025NIH's project files
P30CA016672Cancer Center Support Grant1042,025NIH's project files
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia402,025NIH's project files
P30CA016058Cancer Center Support Grant282,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award232,025NIH's project files
P50CA171963Specialized Program of Research Excellence (SPORE) in Leukemia192,025NIH's project files
P01CA206978Comprehensive dissection of the CLL genome & phenome to improve patient outcomes182,025NIH's project files
P30CA006973Regional Oncology Research Center182,025NIH's project files
P30CA015704Cancer Center Support Grant172,025NIH's project files
R01CA155010Personal tumor neoantigens for immunity against chronic lymphocytic leukemia162,025NIH's project files

Papers 6124

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42806564PubTator, text miningPubMed
42804857PubTator, text miningPubMed
42796004PubTator, text miningPubMed
42782774PubTator, text miningPubMed
42776834PubTator, text miningPubMed
42742668PubTator, text miningPubMed
42741937PubTator, text miningPubMed
42740583PubTator, text miningPubMed
42728663PubTator, text miningPubMed
42727885PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license