Gene · 23462
HEY1: hes related family bHLH transcription factor with YRPW motif 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HEY1: hes related family bHLH transcription factor with YRPW motif 1. Genes, record 23462. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23462
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | 304 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 15078 | Q9Y5J3 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15078 | Q9Y5J3 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15078 | Q9Y5J3 | Espacenet |
| EP 4491229 A2 | 2025-01-15 | 100 | Q9Y5J3 | Espacenet |
| WO 2024230934 A1 | 2024-11-14 | 225 | Q9Y5J3 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14917 | Q9Y5J3 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 5863 | Q9Y5J3 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 37944 | Q9Y5J3 | Espacenet |
| JP 2022092366 A | 2022-06-22 | 580 | Q9Y5J3 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 140915 | Q9Y5J3 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,288
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HEY1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 25 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 21 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 10 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 9 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 7 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 7 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 6 | 2025 |
| P30CA006516 | Dana-Farber/Harvard Cancer Center | 5 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 5 | 2025 |
| P30CA168524 | The University of Kansas Cancer Center | 5 | 2025 |
1 to 10 of 2,288Source NIH's project files
See all 2,288 nih grantsPapers3,005
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Functional interplay between LSD1 and HDAC6 supports malignant phenotypes in breast cancer models and is associated with notch-related protein changes. | Cell Signal | 2026 | 42805446 | PubTator, text mining | PubMed |
| Establishment of a cell line-based 3-D coculture model of the endometrium for studying endometrial receptivity. | Am J Physiol Cell Physiol | 2026 | 42775555 | PubTator, text mining | PubMed |
| Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte-to-DC Differentiation Via Microbiota-Associated IAA. | Adv Sci (Weinh) | 2026 | 42750356 | PubTator, text mining | PubMed |
| PM10 Exposure Impairs Differentiation and Induces Inflammation in Human Small Airway Epithelial Cells Cultured at the Air-Liquid Interface. | Tuberc Respir Dis (Seoul) | 2026 | 42693576 | PubTator, text mining | PubMed |
| MLL1 Regulates T-Cell Phenotype via Notch Signaling During Abdominal Aortic Aneurysm Development. | Arterioscler Thromb Vasc Biol | 2026 | 42619610 | PubTator, text mining | PubMed |
| Integrin-Associated Signalling Regulates Jagged1-Induced Osteogenic Differentiation of Human Dental Pulp Stem Cells. | Int Dent J | 2026 | 42607518 | PubTator, text mining | PubMed |
| Anandamide modulates NOTCH1 signalling and inflammatory responses during human endometrial stromal cell decidualization. | Reproduction | 2026 | 42606559 | PubTator, text mining | PubMed |
| Bioinformatics and experimental studies of atherosclerosis-related endothelial dysfunction genes in renal calculi and exploration of their molecular mechanisms. | PLoS One | 2026 | 42550868 | PubTator, text mining | PubMed |
| Plectin 1d Isoform as a Potential Regulator of Metastatic Progression in Papillary Thyroid Carcinoma. | Int J Mol Sci | 2026 | 42511682 | PubTator, text mining | PubMed |
| Ion-Responsive Microneedles Delivering Subtype-Specific Mitochondrial Extracellular Vesicles from HEY1⁺ Cardiomyocytes for Cardiac Repair in Bama Minipigs with Myocardial Ischemia-Reperfusion Injury. | Theranostics | 2026 | 42370197 | PubTator, text mining | PubMed |
1 to 10 of 3,005
See all 3,005 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23462
GET https://conductscience.org/api/genes/v1/23462/patents?page=2