Gene · 23493
HEY2: hes related family bHLH transcription factor with YRPW motif 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HEY2: hes related family bHLH transcription factor with YRPW motif 2. Genes, record 23493. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23493
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UBP5 | Hairy/enhancer-of-split related with YRPW motif protein 2 | 337 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48655 | Q9UBP5 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15079 | Q9UBP5 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29540 | Q9UBP5 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15079 | Q9UBP5 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15079 | Q9UBP5 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 29540 | Q9UBP5 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14918 | Q9UBP5 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 29540 | Q9UBP5 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 37947 | Q9UBP5 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 140918 | Q9UBP5 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,433
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HEY2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| T32HL007208 | Integrated, Multidisciplinary Training in Cardiovascular Research | 5 | 2025 |
| U54CA118638 | 1/3 Morehouse School of Medicine/Tuskegee University/University of Alabama at Birmingham O'Neal Comprehensive Cancer Center Partnership | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 4 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 4 | 2025 |
| T32HL007381 | Cardiovascular Sciences Training Grant | 4 | 2025 |
1 to 10 of 1,433Source NIH's project files
See all 1,433 nih grantsPapers1,569
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Establishment of a cell line-based 3-D coculture model of the endometrium for studying endometrial receptivity. | Am J Physiol Cell Physiol | 2026 | 42775555 | PubTator, text mining | PubMed |
| MLL1 Regulates T-Cell Phenotype via Notch Signaling During Abdominal Aortic Aneurysm Development. | Arterioscler Thromb Vasc Biol | 2026 | 42619610 | PubTator, text mining | PubMed |
| Identification of genes differentially expressed in granulosa cells from women with high vs. low ovarian responsiveness. | Front Reprod Health | 2026 | 42358728 | PubTator, text mining | PubMed |
| Relationship of oxytocin and cortisol response to psychosocial stress in children and adolescents with anxiety disorders. | Sci Rep | 2026 | 41888549 | PubTator, text mining | PubMed |
| ESRP1-Associated CD44 Alternative Splicing Stratifies Epithelial-Mesenchymal Identity States in a Non-Transformed Human Cell System. | Curr Issues Mol Biol | 2026 | 41751394 | PubTator, text mining | PubMed |
| A Comprehensive Adenoid Cystic Carcinoma-Derived Organoid Platform for Disease Modeling and Drug Screening Captures Interpatient Heterogeneity. | Cells | 2026 | 41744826 | PubTator, text mining | PubMed |
| Prdm16 Amplifies Notch Signaling and Suppresses Venous Lineage Specification to Prevent Arteriovenous Malformations During Vascular Development. | Arterioscler Thromb Vasc Biol | 2026 | 41711027 | PubTator, text mining | PubMed |
| A small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis. | Nat Commun | 2026 | 41547848 | PubTator, text mining | PubMed |
| Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes. | Nat Commun | 2026 | 41526351 | PubTator, text mining | PubMed |
| GATA6 inhibits the periodontitis progression through regulating the Notch signaling pathway. | Odontology | 2026 | 40788377 | PubTator, text mining | PubMed |
1 to 10 of 1,569
See all 1,569 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23493
GET https://conductscience.org/api/genes/v1/23493/patents?page=2