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Gene · 2350

FOLR2: folate receptor beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FOLR2: folate receptor beta. Genes, record 2350. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2350

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Gene

Symbol
FOLR2
HGNC
Name
folate receptor beta
HGNC
NCBI Gene ID
2350
NCBI Gene
HGNC ID
HGNC:3793
HGNC
Ensembl
ENSG00000165457
NCBI Gene
Aliases
BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3, FRbeta, FRβ
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P14207Folate receptor beta2555Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446495P14207Espacenet
EP 4650780 A22025-11-193866P14207Espacenet
EP 4641201 A22025-10-293435P14207Espacenet
JP 2025147176 A2025-10-065521P14207Espacenet
JP 2025529142 A2025-09-041608P14207Espacenet
JP 2025529142 A2025-09-046412P14207Espacenet
US 12371689 B22025-07-291608P14207Espacenet
US 12371689 B22025-07-296412P14207Espacenet
JP 2025517969 A2025-06-123435P14207Espacenet
JP 2025517970 A2025-06-123866P14207Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants757

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFOLR2 papersNewest fiscal year
T32CA009531Training Program in the Biology of Cancer122025
P30CA022453CANCER CENTER SUPPORT GRANT72025
P01CA254859Intraoperative Near Infrared Molecular Imaging of Lung Cancer62025
P30CA023168Cancer Center Support Grant42025
R01CA250469Therapeutic Targeting Mitochondrial C1 Metabolism42025
R01NS034239Neuroprotective Immunity and HIV Dementia42025
P30CA124435Stanford Cancer Institute32025
R01AR074096Monitoring Disease in Lupus32025
P30AG028716Duke Claude D. Pepper Older Americans Independence Center22025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 757Source NIH's project files

See all 757 nih grants

Papers1,286

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Impaired antigen clearance of macrophages associates with heart failure and non-obstructive azoospermia: insights from transcriptomics, in silico knockout, and in vitro validation.Front Immunol202642812170PubTator, text miningPubMed
Genetic variation in macrophage-restricted FOLR2 is associated with neurodevelopmental and reproductive immune phenotypes.Front Immunol202642787123PubTator, text miningPubMed
Rethinking the Benign Nature of Class II Lupus Nephritis.bioRxiv202642779877PubTator, text miningPubMed
A proinflammatory FOLR2-positive macrophage subtype promotes cutaneous and renal damage in systemic lupus erythematosus.J Invest Dermatol202642716208PubTator, text miningPubMed
Targeting Folate Receptors for the Detection and Selective Treatment of Cancer: Advanced Precision Oncology in Practice.Int J Biol Sci202642694955PubTator, text miningPubMed
Dynamic remodeling of the pancreas immune landscape in obesity.Nat Commun202642660905PubTator, text miningPubMed
The FOLR2-IRF2BP2 axis mediates erythropoiesis impairment by excess folic acid in myelodysplastic neoplasms.Leukemia202642575953PubTator, text miningPubMed
Single-cell transcriptomic profiling of immune microenvironment remodeling in unresectable hepatocellular carcinoma after TACE combined therapies.Int Immunopharmacol202642480323PubTator, text miningPubMed
Folic acid-functionalized PEGylated magnetic nanocarriers for targeted delivery of curcumin to inflamed tissues.J Pharm Pharmacol202642418839PubTator, text miningPubMed
Immune activation induced by FOLR2+ decidual macrophage deficiency impairs decidualization and angiogenesis in spontaneous abortion.Front Immunol202642416064PubTator, text miningPubMed

1 to 10 of 1,286

See all 1,286 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2350

GET https://conductscience.org/api/genes/v1/2350/patents?page=2