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FOS: Fos proto-oncogene, AP-1 transcription factor subunit

1 protein, 118 patents, 0 drugs, 0 trials, 17,314 NIH grants and 34,352 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFOSHGNC
NameFos proto-oncogene, AP-1 transcription factor subunitHGNC
NCBI Gene ID2353NCBI Gene
HGNC IDHGNC:3796HGNC
EnsemblENSG00000170345NCBI Gene
AliasesAP-1, C-FOS, c-fos, p55NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01100Protein c-Fos3803Ensembl, GeneID, HGNCUniProt

Patents 118

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194407P01100Espacenet
EP 4641201 A22025-10-293953P01100Espacenet
EP 4641202 A22025-10-294807P01100Espacenet
JP 2025156332 A2025-10-1432P01100Espacenet
JP 2025147176 A2025-10-0614969P01100Espacenet
JP 2025517969 A2025-06-123953P01100Espacenet
JP 2025517970 A2025-06-124407P01100Espacenet
JP 2025032204 A2025-03-1125291P01100Espacenet
JP 2025032204 A2025-03-1125300P01100Espacenet
JP 2025028160 A2025-02-2814969P01100Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 17314

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1062,025NIH's project files
P30CA008748Cancer Center Support Grant702,025NIH's project files
P30CA016058Cancer Center Support Grant322,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program272,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)242,025NIH's project files
P30CA006973Regional Oncology Research Center232,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant232,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant232,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award232,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant222,025NIH's project files

Papers 34352

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820924PubTator, text miningPubMed
42818582PubTator, text miningPubMed
42812065PubTator, text miningPubMed
42810776PubTator, text miningPubMed
42808587PubTator, text miningPubMed
42801669PubTator, text miningPubMed
42801008PubTator, text miningPubMed
42793398PubTator, text miningPubMed
42793037PubTator, text miningPubMed
42792654PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license