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Gene · 23532

PRAME: PRAME nuclear receptor transcriptional regulator

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PRAME: PRAME nuclear receptor transcriptional regulator. Genes, record 23532. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23532

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Gene

Symbol
PRAME
HGNC
Name
PRAME nuclear receptor transcriptional regulator
HGNC
NCBI Gene ID
23532
NCBI Gene
HGNC ID
HGNC:9336
HGNC
Ensembl
ENSG00000185686
NCBI Gene
Aliases
CT130, MAPE, OIP-4, OIP4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P78395Melanoma antigen preferentially expressed in tumors5090Ensembl, GeneID, HGNC

Source UniProt

Patents285

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026209996 A12026-10-0817P78395Espacenet
WO 2026210006 A12026-10-0817P78395Espacenet
WO 2026190687 A12026-09-17291P78395Espacenet
EP 4803546 A12026-09-0938P78395Espacenet
WO 2026167100 A12026-08-1379P78395Espacenet
JP 2026095514 A2026-06-11943P78395Espacenet
JP 2026095514 A2026-06-11944P78395Espacenet
JP 2026095514 A2026-06-11945P78395Espacenet
JP 2026095514 A2026-06-11946P78395Espacenet
JP 2026095514 A2026-06-11947P78395Espacenet

1 to 10 of 285

See all 285 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants729

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRAME papersNewest fiscal year
P30CA008748Cancer Center Support Grant312025
P30CA016672Cancer Center Support Grant162025
P30EY014801Miami Center for Vision Research142025
P50CA126752SPORE in Lymphoma142025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant102025
P01CA018029Adult Leukemia Research Center62025
P30CA240139The Sylvester Cancer Center Support Grant62025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center52025
P30EY026877Stanford Vision Research Core52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025

1 to 10 of 729Source NIH's project files

See all 729 nih grants

Papers1,874

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular Characterization of Sclerosing Nevi With Pseudomelanomatous Features.J Cutan Pathol202642816143PubTator, text miningPubMed
Papillary endothelial hyperplasia in late post-radiation or late post-operative breast hematomas mimicking angiosarcoma.Hum Pathol202642815784PubTator, text miningPubMed
Search for leukemia-restricted targets: a new paradigm for precision immunotherapy in acute myeloid leukemia.Haematologica202642779343PubTator, text miningPubMed
Immunohistochemical Predictors in Head and Neck Mucosal Melanoma.Head Neck Pathol202642771296PubTator, text miningPubMed
PRAME as a Diagnostic Adjunct in Clear Cell Sarcoma.Appl Immunohistochem Mol Morphol202642746728PubTator, text miningPubMed
Performance of PRAME Immunohistochemistry in Distinguishing Classic Hodgkin Lymphoma from Anaplastic Large Cell Lymphoma and T-Cell Lymphoma.Cancers (Basel)202642738395PubTator, text miningPubMed
Top advances of the year in autologous cellular therapy in melanoma and solid tumors.Cancer202642734903PubTator, text miningPubMed
Histopathologic, Genomic, and Clinical Characteristics of Primary Cutaneous Melanocytic Tumors With Concomitant NRAS Q61 and IDH1 R132C Mutations.Mod Pathol202642710739PubTator, text miningPubMed
Sentinel lymph node biopsy in melanoma: pathologic evaluation and diagnostic considerations.J Pathol Transl Med202642675997PubTator, text miningPubMed
Integrated Immunotherapy Target Atlas for Ewing Sarcoma.Cancer Genomics Proteomics202642674817PubTator, text miningPubMed

1 to 10 of 1,874

See all 1,874 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/23532

GET https://conductscience.org/api/genes/v1/23532/patents?page=2