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Gene · 2355

FOSL2: FOS like 2, AP-1 transcription factor subunit

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FOSL2: FOS like 2, AP-1 transcription factor subunit. Genes, record 2355. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2355

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Gene

Symbol
FOSL2
HGNC
Name
FOS like 2, AP-1 transcription factor subunit
HGNC
NCBI Gene ID
2355
NCBI Gene
HGNC ID
HGNC:3798
HGNC
Ensembl
ENSG00000075426
NCBI Gene
Aliases
ACED, FLJ23306, FRA2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P15408Fos-related antigen 23260Ensembl, GeneID, HGNC

Source UniProt

Patents54

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446622P15408Espacenet
JP 2025147176 A2025-10-0614972P15408Espacenet
JP 2025032204 A2025-03-1128548P15408Espacenet
JP 2025028160 A2025-02-2814972P15408Espacenet
KR 1020250010750 A2025-01-2114972P15408Espacenet
EP 4461818 A22024-11-1328548P15408Espacenet
JP 2024109657 A2024-08-1414811P15408Espacenet
JP 2024519218 A2024-05-09117P15408Espacenet
KR 1020240005837 A2024-01-1274P15408Espacenet
JP 2023058610 A2023-04-2528548P15408Espacenet

1 to 10 of 54

See all 54 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,429

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFOSL2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
P30CA016672Cancer Center Support Grant142025
P30AG017265USC/UCLA Center on Biodemography and Population Health122025
P30CA016087Cancer Center Support Grant62025
P30CA021765Cancer Center Support Grant (CCSG)62025
P30CA016058Cancer Center Support Grant52025
P30CA046934University of Colorado Cancer Center Support Grant52025
P51OD011092Support for National Primate Research Center52025
ZIABC010309Nuclear Architecture and Disease52025
ZIAES103311Environmental Signaling in Reproduction and Pregnancy52025

1 to 10 of 2,429Source NIH's project files

See all 2,429 nih grants

Papers2,749

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Transcriptional circuits of the glioma microenvironment: FOSL2 as a master regulator of the pathological niche.Genes Dis202742698676PubTator, text miningPubMed
The DCBLD2 super-enhancer drives colorectal cancer progression through FOSL2/JUND-mediated activation of the CD146/AKT/TNFRSF6B pathway.Mol Biomed202642776394PubTator, text miningPubMed
Multi-omics analysis identifies macrophage immunometabolic signatures in ulcerative colitis.Front Cell Infect Microbiol202642755516PubTator, text miningPubMed
Preliminary analysis of chromatin accessibility in osteosarcoma tissues.Clinics (Sao Paulo)202642700546PubTator, text miningPubMed
Integrated Toxicogenomic Analysis Reveals Potential Molecular Signatures Associated with Cadmium-Related Osteoarthritis.Biol Trace Elem Res202642698020PubTator, text miningPubMed
Interleukin13 Ameliorates Hepatocellular Steatosis via IL13Rα1/JNK/FOSL2 Signaling Pathway.Cell Mol Gastroenterol Hepatol202642692359PubTator, text miningPubMed
Driver genomic lesions in MDM2, CDK4, and JUN co-opt targetable super-enhancer networks to impose liposarcomagenic core regulatory circuitry.J Adv Res202642674282PubTator, text miningPubMed
Hypoxia-Driven Mechanisms in Ischemic Heart Failure: A Bioinformatics, Machine Learning and Bayesian Network Study.Cardiovasc Toxicol202642645701PubTator, text miningPubMed
Multi-omics integration identifies VIM and LGALS3 as apoptosis-associated genes in astrocytes after traumatic brain injury.Neuroscience202642617790PubTator, text miningPubMed
PhiKan 083 Inhibits MYCN Expression in Liver Cancer Cells Independent of p53 Pathways.ACS Pharmacol Transl Sci202642614793PubTator, text miningPubMed

1 to 10 of 2,749

See all 2,749 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2355

GET https://conductscience.org/api/genes/v1/2355/patents?page=2