Gene · 23552
CDK20: cyclin dependent kinase 20
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CDK20: cyclin dependent kinase 20. Genes, record 23552. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23552
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8IZL9 | Cyclin-dependent kinase 20 | 346 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents9
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 5031 | Q8IZL9 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5031 | Q8IZL9 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 21292 | Q8IZL9 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 124263 | Q8IZL9 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 1934 | Q8IZL9 | Espacenet |
| JP 2017121240 A | 2017-07-13 | 49771 | Q8IZL9 | Espacenet |
| JP 2015518704 A | 2015-07-06 | 49771 | Q8IZL9 | Espacenet |
| JP 2004511204 A | 2004-04-15 | 36 | Q8IZL9 | Espacenet |
| WO 0181555 A2 | 2001-11-01 | 18 | Q8IZL9 | Espacenet |
Drugs4
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| AT-7519 | CHEMBL445813 | Cyclin-dependent kinase inhibitor | INHIBITOR | ChEMBL |
| AZD-5438 | CHEMBL488436 | Cyclin-dependent kinase inhibitor | INHIBITOR | ChEMBL |
| PHA-793887 | CHEMBL1230607 | Cyclin-dependent kinase inhibitor | INHIBITOR | ChEMBL |
| RONICICLIB | CHEMBL4442620 | Cyclin-dependent kinase inhibitor | INHIBITOR | ChEMBL |
Trials7
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT02522910 | RONICICLIB | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT02161419 | RONICICLIB | PHASE2 | ClinicalTrials.gov | |
| NCT01652144 | AT-7519 | PHASE2 | ClinicalTrials.gov | |
| NCT01627054 | AT-7519 | PHASE2 | ClinicalTrials.gov | |
| NCT01573338 | RONICICLIB | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT01188252 | RONICICLIB | PHASE1 | ClinicalTrials.gov | |
| NCT01183949 | AT-7519 | PHASE1/PHASE2 | ClinicalTrials.gov |
NIH grants1,007
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CDK20 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| R01HL058506 | G Protein-Coupled Receptor Regulation in Airway Myocytes | 6 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 3 | 2025 |
| P01CA019014 | Viral Oncogenesis, Latency, and Replication | 2 | 2025 |
| P01CA066996 | Development of Novel Therapeutic Strategies in Human Leukemias | 2 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 2 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 2 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 2 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
1 to 10 of 1,007Source NIH's project files
See all 1,007 nih grantsPapers1,583
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular simulation reveals spontaneous allosteric binding of BMS-357075 to human cyclin-dependent kinase 20. | Int J Biol Macromol | 2026 | 42805525 | PubTator, text mining | PubMed |
| Bi-allelic variants in CDK20 cause a severe ciliopathy with midline brain and facial anomalies. | Am J Hum Genet | 2026 | 42409022 | PubTator, text mining | PubMed |
| Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus. | Analyst | 2026 | 42312723 | PubTator, text mining | PubMed |
| Beyond the hype: navigating the real-world applications of artificial intelligence (AI) in healthcare. | Med Rev (2021) | 2026 | 41783894 | PubTator, text mining | PubMed |
| Putative Fusion-Associated Small Transmembrane (FAST) Proteins Encoded by Viruses of Pistolviridae, Order Ghabrivirales, Identified from In Silico Analyses. | Viruses | 2026 | 41754536 | PubTator, text mining | PubMed |
| Unbiased cleavage site prediction uncovers viral antagonism of host innate immunity by SARS-CoV-2 3C-like protease. | JCI Insight | 2026 | 41729072 | PubTator, text mining | PubMed |
| AlphaFold2 Insights into c-Abl Transactivation by Adaptor c-Crk or Abi-1: Structural Forms, Active Site Types, and Multiple SH3-PxxPxK/R Interactions. | Genes Cells | 2026 | 41618774 | PubTator, text mining | PubMed |
| Enhancing gene therapy vectors manufacturing: CEBPA as a master regulator of rAAV biogenesis. | J Biol Eng | 2026 | 41559702 | PubTator, text mining | PubMed |
| Quantum chemical optimization and residue-specific stabilization of CDK20 inhibitors in hepatocellular carcinoma. | Mol Divers | 2026 | 40928680 | PubTator, text mining | PubMed |
| Activation of the ciliary kinase CDKL5 is mediated by the cyclin-dependent kinase CDK20/LF2 to control flagellar length. | PLoS Biol | 2025 | 41385589 | PubTator, text mining | PubMed |
1 to 10 of 1,583
See all 1,583 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23552
GET https://conductscience.org/api/genes/v1/23552/grants?page=2