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Gene · 23552

CDK20: cyclin dependent kinase 20

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDK20: cyclin dependent kinase 20. Genes, record 23552. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23552

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Gene

Symbol
CDK20
HGNC
Name
cyclin dependent kinase 20
HGNC
NCBI Gene ID
23552
NCBI Gene
HGNC ID
HGNC:21420
HGNC
Ensembl
ENSG00000156345
NCBI Gene
Aliases
CCRK, CDCH, LMCTS, LMDCS, P42, PNQALRE, p42
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IZL9Cyclin-dependent kinase 203460Ensembl, GeneID, HGNC

Source UniProt

Patents9

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-295031Q8IZL9Espacenet
JP 2025517969 A2025-06-125031Q8IZL9Espacenet
US 11446398 B22022-09-2021292Q8IZL9Espacenet
JP 2022524081 A2022-04-27124263Q8IZL9Espacenet
US 11078247 B22021-08-031934Q8IZL9Espacenet
JP 2017121240 A2017-07-1349771Q8IZL9Espacenet
JP 2015518704 A2015-07-0649771Q8IZL9Espacenet
JP 2004511204 A2004-04-1536Q8IZL9Espacenet
WO 0181555 A22001-11-0118Q8IZL9Espacenet

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AT-7519CHEMBL445813Cyclin-dependent kinase inhibitorINHIBITORChEMBL
AZD-5438CHEMBL488436Cyclin-dependent kinase inhibitorINHIBITORChEMBL
PHA-793887CHEMBL1230607Cyclin-dependent kinase inhibitorINHIBITORChEMBL
RONICICLIBCHEMBL4442620Cyclin-dependent kinase inhibitorINHIBITORChEMBL

Trials7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02522910RONICICLIBPHASE1/PHASE2ClinicalTrials.gov
NCT02161419RONICICLIBPHASE2ClinicalTrials.gov
NCT01652144AT-7519PHASE2ClinicalTrials.gov
NCT01627054AT-7519PHASE2ClinicalTrials.gov
NCT01573338RONICICLIBPHASE1/PHASE2ClinicalTrials.gov
NCT01188252RONICICLIBPHASE1ClinicalTrials.gov
NCT01183949AT-7519PHASE1/PHASE2ClinicalTrials.gov

NIH grants1,007

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDK20 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
R01HL058506G Protein-Coupled Receptor Regulation in Airway Myocytes62025
P30CA016086Cancer Center Support Grant32025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025
P01CA019014Viral Oncogenesis, Latency, and Replication22025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA008748Cancer Center Support Grant22025
P30CA021765Cancer Center Support Grant (CCSG)22025

1 to 10 of 1,007Source NIH's project files

See all 1,007 nih grants

Papers1,583

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular simulation reveals spontaneous allosteric binding of BMS-357075 to human cyclin-dependent kinase 20.Int J Biol Macromol202642805525PubTator, text miningPubMed
Bi-allelic variants in CDK20 cause a severe ciliopathy with midline brain and facial anomalies.Am J Hum Genet202642409022PubTator, text miningPubMed
Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus.Analyst202642312723PubTator, text miningPubMed
Beyond the hype: navigating the real-world applications of artificial intelligence (AI) in healthcare.Med Rev (2021)202641783894PubTator, text miningPubMed
Putative Fusion-Associated Small Transmembrane (FAST) Proteins Encoded by Viruses of Pistolviridae, Order Ghabrivirales, Identified from In Silico Analyses.Viruses202641754536PubTator, text miningPubMed
Unbiased cleavage site prediction uncovers viral antagonism of host innate immunity by SARS-CoV-2 3C-like protease.JCI Insight202641729072PubTator, text miningPubMed
AlphaFold2 Insights into c-Abl Transactivation by Adaptor c-Crk or Abi-1: Structural Forms, Active Site Types, and Multiple SH3-PxxPxK/R Interactions.Genes Cells202641618774PubTator, text miningPubMed
Enhancing gene therapy vectors manufacturing: CEBPA as a master regulator of rAAV biogenesis.J Biol Eng202641559702PubTator, text miningPubMed
Quantum chemical optimization and residue-specific stabilization of CDK20 inhibitors in hepatocellular carcinoma.Mol Divers202640928680PubTator, text miningPubMed
Activation of the ciliary kinase CDKL5 is mediated by the cyclin-dependent kinase CDK20/LF2 to control flagellar length.PLoS Biol202541385589PubTator, text miningPubMed

1 to 10 of 1,583

See all 1,583 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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