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Gene · 2358

FPR2: formyl peptide receptor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FPR2: formyl peptide receptor 2. Genes, record 2358. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2358

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Gene

Symbol
FPR2
HGNC
Name
formyl peptide receptor 2
HGNC
NCBI Gene ID
2358
NCBI Gene
HGNC ID
HGNC:3827
HGNC
Ensembl
ENSG00000171049
NCBI Gene
Aliases
ALX, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P25090N-formyl peptide receptor 235113Ensembl, GeneID, HGNC

Source UniProt

Patents91

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446616P25090Espacenet
JP 2026004568 A2026-01-1446617P25090Espacenet
EP 4641201 A22025-10-296258P25090Espacenet
JP 2025529142 A2025-09-041610P25090Espacenet
US 12371689 B22025-07-291610P25090Espacenet
JP 2025517969 A2025-06-126258P25090Espacenet
US 12188935 B22025-01-0711P25090Espacenet
WO 2024252368 A22024-12-12164P25090Espacenet
US 11446398 B22022-09-2032751P25090Espacenet
US 11446398 B22022-09-2032752P25090Espacenet

1 to 10 of 91

See all 91 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,697

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFPR2 papersNewest fiscal year
ZIAAI000904Staphylococcal pathogenesis202025
ZIAAI000615Molecular Analysis Of Leukocyte Activation By Chemoattractants182025
P20GM103474MT INBRE: A Multidisciplinary Research Network72025
R35GM128641Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation72025
P30CA016672Cancer Center Support Grant62025
K12HD047349Pediatric Critical Care and Trauma Scientist Development Program (PCCTSDP)52025
P30CA008748Cancer Center Support Grant52025
P30CA118100University of New Mexico Cancer Center Support Grant52025
R01DE022971THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATION52025
R01DK073368Mechanisms of Compartmentalized cAMP Signaling52025

1 to 10 of 1,697Source NIH's project files

See all 1,697 nih grants

Papers3,281

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Coassembled peptide nanoparticles enable stage-specific diagnosis and targeted therapy of hepatic fibrosis by inhibiting macrophage-driven inflammation.Biomaterials202742585841PubTator, text miningPubMed
Fast and slow gene expression changes in blood following acute social stress.Brain Behav Immun Health202642824708PubTator, text miningPubMed
Resolution Pathways in the Context of Viral Infections.Curr Top Microbiol Immunol202642814136PubTator, text miningPubMed
Resolution of inflammation: A novel therapeutic paradigm for rheumatoid arthritis and its comorbidities.Pharmacol Res202642810630PubTator, text miningPubMed
Skill-File-Guided Virtual Screening: A Single-Target Formyl Peptide Receptor 2 Case Study of Large-Language-Model-Coordinated Physics and Diffusion Docking.Comput Struct Biotechnol J202642719324PubTator, text miningPubMed
GTPase RAB31 supports ANXA1-driven macrophage education through clathrin-mediated endocytosis to suppress antitumor immunity.J Immunother Cancer202642686375PubTator, text miningPubMed
Lipoxin A4 attenuates Helicobacter pylori-induced gastric mucosal inflammation through promoting inflammatory resolution.Tissue Cell202642659813PubTator, text miningPubMed
Building Blocks of 2,3-Diaminopropionic Acid Functionalized with an Oxa-Acid Spacer Shift the Functional Profile of Human Cathelicidin LL-37: Enhanced Enzymatic Stability and Selective Suppression of Neutrophil Degranulation.
Pharmaceuticals (Basel)202642653651PubTator, text miningPubMed
Transcriptomic Markers of Immunosenescence in Cynomolgus Macaques: A Pilot Study.Genes (Basel)202642650137PubTator, text miningPubMed
The peptide Ac2-26 preserves mitochondrial function and neuronal survival in human retinal cells and organoids under hyperglycemic and inflammatory stress.Biomed Pharmacother202642632302PubTator, text miningPubMed

1 to 10 of 3,281

See all 3,281 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2358

GET https://conductscience.org/api/genes/v1/2358/patents?page=2