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RIGI: RNA sensor RIG-I

1 protein, 57 patents, 0 drugs, 0 trials, 6,482 NIH grants and 13,728 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRIGIHGNC
NameRNA sensor RIG-IHGNC
NCBI Gene ID23586NCBI Gene
HGNC IDHGNC:19102HGNC
EnsemblENSG00000107201NCBI Gene
AliasesDDX58, DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1, RLR-1, SGMRT2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O95786Antiviral innate immune response receptor RIG-I92544Ensembl, GeneID, HGNCUniProt

Patents 57

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026058346 A2026-04-03311O95786Espacenet
JP 2026021469 A2026-02-10311O95786Espacenet
WO 2025252547 A12025-12-1132O95786Espacenet
EP 4660322 A12025-12-1032O95786Espacenet
JP 2025138811 A2025-09-2598O95786Espacenet
EP 4613276 A22025-09-10311O95786Espacenet
JP 2025120300 A2025-08-1598O95786Espacenet
JP 2025081374 A2025-05-27311O95786Espacenet
JP 2025038035 A2025-03-184483O95786Espacenet
WO 2025016918 A12025-01-2332O95786Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6482

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant232,025NIH's project files
P30DK034854Integrated Epithelial and Muscosal Biology222,025NIH's project files
P30CA016086Cancer Center Support Grant212,025NIH's project files
P01CA019014Viral Oncogenesis, Latency, and Replication202,025NIH's project files
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged192,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital182,025NIH's project files
T32AI007647Training Program in Mechanisms of Virus-Host Interactions182,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award182,025NIH's project files
P51OD011132Emory National Primate Research Center172,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation162,025NIH's project files

Papers 13728

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822072PubTator, text miningPubMed
42822021PubTator, text miningPubMed
42818735PubTator, text miningPubMed
42802076PubTator, text miningPubMed
42801537PubTator, text miningPubMed
42800308PubTator, text miningPubMed
42797836PubTator, text miningPubMed
42792593PubTator, text miningPubMed
42789514PubTator, text miningPubMed
42787502PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license