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Gene · 23604

DAPK2: death associated protein kinase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DAPK2: death associated protein kinase 2. Genes, record 23604. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23604

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Gene

Symbol
DAPK2
HGNC
Name
death associated protein kinase 2
HGNC
NCBI Gene ID
23604
NCBI Gene
HGNC ID
HGNC:2675
HGNC
Ensembl
ENSG00000035664
NCBI Gene
Aliases
DRP-1, DRP1, MGC119312
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UIK4Death-associated protein kinase 237011Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443408Q9UIK4Espacenet
JP 2026004568 A2026-01-1443409Q9UIK4Espacenet
EP 4641201 A22025-10-291555Q9UIK4Espacenet
JP 2025529142 A2025-09-041214Q9UIK4Espacenet
US 12371689 B22025-07-291214Q9UIK4Espacenet
JP 2025517969 A2025-06-121555Q9UIK4Espacenet
JP 2025032204 A2025-03-1127091Q9UIK4Espacenet
JP 2025032204 A2025-03-1127096Q9UIK4Espacenet
EP 4461818 A22024-11-1327091Q9UIK4Espacenet
EP 4461818 A22024-11-1327096Q9UIK4Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,026

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDAPK2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant42025
T32CA009594Multi-Disciplinary Training Grant in Cancer Research42025
P30CA008748Cancer Center Support Grant32025
P30CA016058Cancer Center Support Grant32025
P30CA016086Cancer Center Support Grant32025
R01DE016572Ceramide Signaling in the Regulation of Head & Neck Cancer Cell Death and Therapy32025
P20GM103440Nevada IDeA Networks of Biomedical Research Excellence (INBRE)22025
P30AG024827Pittsburgh Older Americans Independence Center22025
P30AG050886Comparative Bioenergetics of Aging22025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025

1 to 10 of 1,026Source NIH's project files

See all 1,026 nih grants

Papers1,471

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
circNfix attenuates acute kidney injury by driving m6A-dependent degradation of YTHDF2 to stabilize DAPK2 mRNA.Clin Sci (Lond)202642742123PubTator, text miningPubMed
SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation.Proc Natl Acad Sci U S A202642636358PubTator, text miningPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circ Res202642594169PubTator, text miningPubMed
A role for noncoding RNAs and alternative splicing in the regulation of neutrophil activation and gene expression in systemic lupus erythematosus.J Leukoc Biol202642460818PubTator, text miningPubMed
Integrated multi-omics strategies for identifying novel therapies in psoriasis.Bioinformatics202642209436PubTator, text miningPubMed
VGLL3 Regulates DAPK2-Mediated Autophagy During Osteoblast Differentiation.Biofactors202642052791PubTator, text miningPubMed
A small-molecule stabilizer of the calpastatin-calpain-2 complex restores mitochondrial function and mitigates neurodegeneration.Sci Adv202641894510PubTator, text miningPubMed
The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets.Cells202641892342PubTator, text miningPubMed
The histone acylation network: emerging therapeutic targets for remodeling the epigenetic landscape in pancreatic ductal adenocarcinoma.Cell Oncol (Dordr)202641874858PubTator, text miningPubMed
Prophylactic C-terminal occludin-derived peptide attenuates LPS-induced airway inflammation via barrier preservation and mitochondrial ROS regulation.Redox Biol202641830671PubTator, text miningPubMed

1 to 10 of 1,471

See all 1,471 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/23604

GET https://conductscience.org/api/genes/v1/23604/patents?page=2