Gene · 23645
PPP1R15A: protein phosphatase 1 regulatory subunit 15A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PPP1R15A: protein phosphatase 1 regulatory subunit 15A. Genes, record 23645. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23645
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75807 | Protein phosphatase 1 regulatory subunit 15A | 674 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 205 | O75807 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4299 | O75807 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 205 | O75807 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 33959 | O75807 | Espacenet |
| JP 2025505936 A | 2025-03-05 | 5 | O75807 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4299 | O75807 | Espacenet |
| EP 4472664 A1 | 2024-12-11 | 5 | O75807 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 33959 | O75807 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 7878 | O75807 | Espacenet |
| US 11873486 B2 | 2024-01-16 | 27 | O75807 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,798
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PPP1R15A papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| R01CA109182 | Functional Determinants of Metastatic Dormancy | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 7 | 2025 |
| ZIAHD001010 | Mechanism and Regulation of Eukaryotic Protein Synthesis | 7 | 2025 |
| R01DK060596 | Translational control by nutrients | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
1 to 10 of 1,798Source NIH's project files
See all 1,798 nih grantsPapers2,536
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Synthesis and biological evaluation of cyanoenone- and enone-fused 4-androstene-3,17-dione derivatives against triple-negative breast cancer. | Bioorg Chem | 2026 | 42748754 | PubTator, text mining | PubMed |
| Proteostasis in the regulation of pancreatic islet cell plasticity. | J Diabetes Investig | 2026 | 42723547 | PubTator, text mining | PubMed |
| Enhancing lysosome function via TFEB activation reduces lipofuscin-like granules in the retinal pigment epithelium. | Exp Eye Res | 2026 | 42637174 | PubTator, text mining | PubMed |
| Patient-specific iPSC-derived ECs identify QKI-7 as a key regulator of endothelial dysfunction and potential therapeutic target in diabetes. | Stem Cells Transl Med | 2026 | 42560887 | PubTator, text mining | PubMed |
| GRHAL1, a novel lncRNA, regulates HIV-1 gene expression by modulating Tat- and Sp1-mediated HIV-1 LTR activation. | J Gen Virol | 2026 | 42391287 | PubTator, text mining | PubMed |
| Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer. | Adv Sci (Weinh) | 2026 | 42371785 | PubTator, text mining | PubMed |
| TDP-43 oxidation and PP1 crosstalk at RNA granule-mitochondria contact sites. | Nat Commun | 2026 | 42248860 | PubTator, text mining | PubMed |
| Integrated transcriptomic profiling of programmed cell death patterns unveils macrophage-hepatocyte crosstalk via THBS1-CD47 axis in hepatic ischemia-reperfusion injury. | Front Immunol | 2026 | 42238567 | PubTator, text mining | PubMed |
| Identification of Autophagy-Associated Molecular Signatures in Osteoarthritis Revealed by Integrative Multi-Omics and Experimental Validation. | Chem Biol Drug Des | 2026 | 42233387 | PubTator, text mining | PubMed |
| Identification and validation of autophagy-related genes in keratoconus and their correlation with immune infiltration. | Medicine (Baltimore) | 2026 | 42216341 | PubTator, text mining | PubMed |
1 to 10 of 2,536
See all 2,536 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23645
GET https://conductscience.org/api/genes/v1/23645/patents?page=2