Gene · 23765
IL17RA: interleukin 17 receptor A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IL17RA: interleukin 17 receptor A. Genes, record 23765. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23765
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96F46 | Interleukin-17 receptor A | 866 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents172
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4731677 A2 | 2026-04-29 | 146 | Q96F46 | Espacenet |
| EP 4705273 A2 | 2026-03-11 | 290 | Q96F46 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50183 | Q96F46 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5347 | Q96F46 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4936 | Q96F46 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6906 | Q96F46 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16691 | Q96F46 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16744 | Q96F46 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2075 | Q96F46 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6706 | Q96F46 | Espacenet |
1 to 10 of 172
See all 172 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| BRODALUMAB | CHEMBL1742996 | Interleukin-17 receptor A antagonist | ANTAGONIST |
Source ChEMBL
Trials47
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT05132231 | BRODALUMAB | ClinicalTrials.gov | ||
| NCT04979520 | BRODALUMAB | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT04622033 | BRODALUMAB | PHASE4 | ClinicalTrials.gov | |
| NCT04614298 | BRODALUMAB | PHASE4 | ClinicalTrials.gov | |
| NCT04533737 | BRODALUMAB | PHASE4 | 2024-01-09 | ClinicalTrials.gov |
| NCT04368403 | BRODALUMAB | PHASE1 | ClinicalTrials.gov | |
| NCT04340076 | BRODALUMAB | PHASE4 | ClinicalTrials.gov | |
| NCT04306315 | BRODALUMAB | PHASE4 | ClinicalTrials.gov | |
| NCT04305327 | BRODALUMAB | PHASE3 | 2024-02-28 | ClinicalTrials.gov |
| NCT04249713 | BRODALUMAB | EARLY_PHASE1 | ClinicalTrials.gov |
1 to 10 of 47
See all 47 trialsNIH grants2,488
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IL17RA papers | Newest fiscal year |
|---|---|---|---|
| R01AI127564 | Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis | 20 | 2025 |
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 18 | 2025 |
| R37DE022550 | Host and Fungal Regulation of Type 17 Immunity to Oral Candidiasis | 16 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30AR075043 | University of Michigan Skin Biology and Diseases Resource-based Center | 10 | 2025 |
| T32AI089474 | Immunology Training Program-Predoctoral | 10 | 2025 |
| ZIAAI000647 | Genes And Gene Products As Immunoadjuvants | 9 | 2025 |
| ZIAAI001175 | Immunopathogenesis of Fungal Infections | 9 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 8 | 2025 |
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 8 | 2025 |
1 to 10 of 2,488Source NIH's project files
See all 2,488 nih grantsPapers3,930
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Therapeutic response to exclusive enteral nutrition correlates with suppressed IL-17 signaling activity and diminished IL-1β secretion in pediatric Crohn's disease. | Front Nutr | 2026 | 42807469 | PubTator, text mining | PubMed |
| Interleukin-17A directly triggers Epstein-Barr virus lytic reactivation in latency I human B-cell models. | J Virol | 2026 | 42782145 | PubTator, text mining | PubMed |
| Secreted ORF8 reprograms macrophages to enhance SARS-CoV-2 infection of lung epithelial cells. | Sci Adv | 2026 | 42758812 | PubTator, text mining | PubMed |
| DYRK kinases phosphorylate IL-17RA at S801. | Serican J Med | 2026 | 42746556 | PubTator, text mining | PubMed |
| Correction to: IL-17A, IL-17RA, and IL-22 as biomarkers in migraine: associations with disease activity and clinical features. | Ir J Med Sci | 2026 | 42734779 | PubTator, text mining | PubMed |
| Endometriosis pain: genes linked to inflammation distinguish symptomatic from asymptomatic disease. | Mol Hum Reprod | 2026 | 42720599 | PubTator, text mining | PubMed |
| Blood proteomics links systemic inflammation with early atherosclerosis in moderate-to-severe atopic dermatitis. | J Invest Dermatol | 2026 | 42716219 | PubTator, text mining | PubMed |
| Silencing SLC52A2 promotes tertiary lymphoid structure formation and inhibits IL-17 pathway to ameliorate melanoma progression. | Apoptosis | 2026 | 42671664 | PubTator, text mining | PubMed |
| IL-17A Restrains Antiviral Immunity to Promote Chikungunya Virus Infection and Pathogenesis in the Heart. | bioRxiv | 2026 | 42620426 | PubTator, text mining | PubMed |
| Interleukin-23 Receptor and Interleukin-17 Receptor A: Splice Variants, Isoforms and Their Relationship With Periodontitis-A Systematic Review and Bioinformatic Analysis. | J Cell Mol Med | 2026 | 42608893 | PubTator, text mining | PubMed |
1 to 10 of 3,930
See all 3,930 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/23765
GET https://conductscience.org/api/genes/v1/23765/patents?page=2