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Gene · 23765

IL17RA: interleukin 17 receptor A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IL17RA: interleukin 17 receptor A. Genes, record 23765. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/23765

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Gene

Symbol
IL17RA
HGNC
Name
interleukin 17 receptor A
HGNC
NCBI Gene ID
23765
NCBI Gene
HGNC ID
HGNC:5985
HGNC
Ensembl
ENSG00000177663
NCBI Gene
Aliases
CANDF5, CD217, CDw217, IL-17RA, IL17R, IMD51, hIL-17R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96F46Interleukin-17 receptor A86610Ensembl, GeneID, HGNC

Source UniProt

Patents172

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4731677 A22026-04-29146Q96F46Espacenet
EP 4705273 A22026-03-11290Q96F46Espacenet
JP 2026004568 A2026-01-1450183Q96F46Espacenet
EP 4650780 A22025-11-195347Q96F46Espacenet
EP 4641201 A22025-10-294936Q96F46Espacenet
JP 2025147176 A2025-10-066906Q96F46Espacenet
JP 2025147176 A2025-10-0616691Q96F46Espacenet
JP 2025147176 A2025-10-0616744Q96F46Espacenet
JP 2025529142 A2025-09-042075Q96F46Espacenet
JP 2025529142 A2025-09-046706Q96F46Espacenet

1 to 10 of 172

See all 172 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
BRODALUMABCHEMBL1742996Interleukin-17 receptor A antagonistANTAGONIST

Source ChEMBL

Trials47

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05132231BRODALUMABClinicalTrials.gov
NCT04979520BRODALUMABEARLY_PHASE1ClinicalTrials.gov
NCT04622033BRODALUMABPHASE4ClinicalTrials.gov
NCT04614298BRODALUMABPHASE4ClinicalTrials.gov
NCT04533737BRODALUMABPHASE42024-01-09ClinicalTrials.gov
NCT04368403BRODALUMABPHASE1ClinicalTrials.gov
NCT04340076BRODALUMABPHASE4ClinicalTrials.gov
NCT04306315BRODALUMABPHASE4ClinicalTrials.gov
NCT04305327BRODALUMABPHASE32024-02-28ClinicalTrials.gov
NCT04249713BRODALUMABEARLY_PHASE1ClinicalTrials.gov

1 to 10 of 47

See all 47 trials

NIH grants2,488

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIL17RA papersNewest fiscal year
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis202025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success182025
R37DE022550Host and Fungal Regulation of Type 17 Immunity to Oral Candidiasis162025
P30CA016672Cancer Center Support Grant112025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center102025
T32AI089474Immunology Training Program-Predoctoral102025
ZIAAI000647Genes And Gene Products As Immunoadjuvants92025
ZIAAI001175Immunopathogenesis of Fungal Infections92025
P30DK058404Molecular and Cellular Basis for Digestive Diseases82025
ZIAAI000646Transgenic Animal Models Of Human Immune Defects82025

1 to 10 of 2,488Source NIH's project files

See all 2,488 nih grants

Papers3,930

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Therapeutic response to exclusive enteral nutrition correlates with suppressed IL-17 signaling activity and diminished IL-1β secretion in pediatric Crohn's disease.Front Nutr202642807469PubTator, text miningPubMed
Interleukin-17A directly triggers Epstein-Barr virus lytic reactivation in latency I human B-cell models.J Virol202642782145PubTator, text miningPubMed
Secreted ORF8 reprograms macrophages to enhance SARS-CoV-2 infection of lung epithelial cells.Sci Adv202642758812PubTator, text miningPubMed
DYRK kinases phosphorylate IL-17RA at S801.Serican J Med202642746556PubTator, text miningPubMed
Correction to: IL-17A, IL-17RA, and IL-22 as biomarkers in migraine: associations with disease activity and clinical features.Ir J Med Sci202642734779PubTator, text miningPubMed
Endometriosis pain: genes linked to inflammation distinguish symptomatic from asymptomatic disease.Mol Hum Reprod202642720599PubTator, text miningPubMed
Blood proteomics links systemic inflammation with early atherosclerosis in moderate-to-severe atopic dermatitis.J Invest Dermatol202642716219PubTator, text miningPubMed
Silencing SLC52A2 promotes tertiary lymphoid structure formation and inhibits IL-17 pathway to ameliorate melanoma progression.Apoptosis202642671664PubTator, text miningPubMed
IL-17A Restrains Antiviral Immunity to Promote Chikungunya Virus Infection and Pathogenesis in the Heart.bioRxiv202642620426PubTator, text miningPubMed
Interleukin-23 Receptor and Interleukin-17 Receptor A: Splice Variants, Isoforms and Their Relationship With Periodontitis-A Systematic Review and Bioinformatic Analysis.J Cell Mol Med202642608893PubTator, text miningPubMed

1 to 10 of 3,930

See all 3,930 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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GET https://conductscience.org/api/genes/v1/23765/patents?page=2