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Gene · 24137

KIF4A: kinesin family member 4A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KIF4A: kinesin family member 4A. Genes, record 24137. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/24137

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Gene

Symbol
KIF4A
HGNC
Name
kinesin family member 4A
HGNC
NCBI Gene ID
24137
NCBI Gene
HGNC ID
HGNC:13339
HGNC
Ensembl
ENSG00000090889
NCBI Gene
Aliases
FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, KIF4G1, MRX100, TMDI, XLID100
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95239Chromosome-associated kinesin KIF4A1,2321Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450884O95239Espacenet
EP 4641201 A22025-10-299713O95239Espacenet
EP 4641202 A22025-10-295619O95239Espacenet
JP 2025517969 A2025-06-129713O95239Espacenet
KR 1020250017231 A2025-02-045619O95239Espacenet
US 11446398 B22022-09-2044330O95239Espacenet
JP 2022092366 A2022-06-22802O95239Espacenet
JP 2022524081 A2022-04-27147301O95239Espacenet
KR 1020210129616 A2021-10-288O95239Espacenet
US 11078247 B22021-08-035893O95239Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants538

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKIF4A papersNewest fiscal year
R35GM119455Mechanisms of Phosphorylation Signaling by Phosphoprotein Phosphatases52025
P20GM113132The Institute for Biomolecular Targeting32025
P30CA008748Cancer Center Support Grant32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA016058Cancer Center Support Grant32025
P30CA023108Cancer Center Support Grant32025
P40OD010440Caenorhabditis Genetics Center32025
P20GM103449Vermont Biomedical Research Network-Vermont INBRE22025
P30CA014520UW Comprehensive Cancer Center Support22025
P30CA016672Cancer Center Support Grant22025

1 to 10 of 538Source NIH's project files

See all 538 nih grants

Papers1,342

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
KIF4A stabilizes TDP43 to promote DNA damage repair and temozolomide resistance in glioblastoma.Biochem Pharmacol202642785594PubTator, text miningPubMed
KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis.Mol Med Rep202642725385PubTator, text miningPubMed
Kinesins in Bladder Cancer: Integrating Molecular Mechanisms and Treatment Approaches.Cell Biol Int202642529891PubTator, text miningPubMed
KIF4A-KIF4B Paralog as a Prognostic Biomarker in Lung Adenocarcinoma.Medicina (Kaunas)202642512966PubTator, text miningPubMed
A bioinformatics analysis of KIF transcriptomic subtyping reveals prognostic heterogeneity and differential therapeutic responses in cervical cancer.Oncol Lett202642491333PubTator, text miningPubMed
Retraction notice to "Integrative PPI network and random forest analysis identifies KIF4A, TOP2A, and ASPM protein macromolecules as novel protein biomarkers in renal carcinoma pathogenesis" [International Journal of Biological Macromolecules 311 (2025) 144058].
Int J Biol Macromol202642486758PubTator, text miningPubMed
ERCC6L in human cancers: oncogenic functions, molecular mechanisms, and clinical implications as a prognostic biomarker and therapeutic target.Front Oncol202642459306PubTator, text miningPubMed
Reanalysis of Public Transcriptomes Reveals Shared Immune Signatures Between Major Depressive Disorder And Dermatomyositis With Single-Cell Context.J Vis Exp202642441576PubTator, text miningPubMed
Acidosis-associated gene signature defines novel subtypes and dual-target therapeutic candidates in breast cancer.J Transl Med202642374456PubTator, text miningPubMed
Low KIF4A expression is associated with gastric cancer progression and aggressive phenotypes.Sci Rep202642251143PubTator, text miningPubMed

1 to 10 of 1,342

See all 1,342 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/24137

GET https://conductscience.org/api/genes/v1/24137/patents