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Gene · 24148

PRPF6: pre-mRNA processing factor 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PRPF6: pre-mRNA processing factor 6. Genes, record 24148. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/24148

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Gene

Symbol
PRPF6
HGNC
Name
pre-mRNA processing factor 6
HGNC
NCBI Gene ID
24148
NCBI Gene
HGNC ID
HGNC:15860
HGNC
Ensembl
ENSG00000101161
NCBI Gene
Aliases
ANT-1, ANT1, C20orf14, Prp6, RP60, SNRNP102, TOM, U5-102K, bB152O15.1, hPrp6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O94906Pre-mRNA-processing factor 694133Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19290O94906Espacenet
JP 2026004568 A2026-01-1460415O94906Espacenet
EP 4650780 A22025-11-192557O94906Espacenet
EP 4641201 A22025-10-292144O94906Espacenet
JP 2025517969 A2025-06-122144O94906Espacenet
JP 2025517970 A2025-06-122557O94906Espacenet
WO 2024214081 A12024-10-17290O94906Espacenet
US 11446398 B22022-09-2066495O94906Espacenet
JP 2022524081 A2022-04-27169466O94906Espacenet
US 11078247 B22021-08-038990O94906Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,100

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRPF6 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)62025
R01NS084412Molecular Genetic Analysis of TORC1 and TORC2 Signaling in Neuronal Maintenance62025
R01GM061721BIOGENESIS OF THE MITOCHONDRIAL INNER MEMBRANE52025
P30AG028740University of Florida Older Americans Independence Center (OAIC)32025
P30CA016087Cancer Center Support Grant32025
P30CA030199Cancer Center Support Grant (CCSG)32025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant32025
P40OD010440Caenorhabditis Genetics Center32025
ZIADK036139structural characterization of bacterial secretion channels32025
ZIANS003127Mechanisms of Autophagy32025

1 to 10 of 1,100Source NIH's project files

See all 1,100 nih grants

Papers1,640

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Mitochondria and associated complexes as therapeutic targets in aging: From biomacromolecular structure-function insights to clinical translation.Mitochondrion202642822579PubTator, text miningPubMed
A Proof-of-Concept Study of Language-Stratified Assessment for Minimal Hepatic Encephalopathy: Integrating the Animal Naming Test and Serum IL-6.Kaohsiung J Med Sci202642625126PubTator, text miningPubMed
Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harb Perspect Biol202642575696PubTator, text miningPubMed
A coupled TOM-TIM22 supercomplex in human mitochondrial protein import.Nat Struct Mol Biol202642538435PubTator, text miningPubMed
Direct coupling of human TOM and TIM22 complexes drives mitochondrial carrier import.Nat Struct Mol Biol202642493623PubTator, text miningPubMed
A comprehensive investigation of social cognition across different stages of psychosis: A staging model comparison including familial high-risk, ultra high-risk, first episode and chronic patients.Schizophr Res202642468292PubTator, text miningPubMed
Mitochondrial Voltage-Dependent Anion Channel: From a Passive Pore to a Cellular Hub Through Protein Complexation.Int J Mol Sci202642450075PubTator, text miningPubMed
The baseline vitreous proteome in rhegmatogenous retinal detachment: a case-control study of proliferative vitreoretinopathy.Sci Rep202642432032PubTator, text miningPubMed
The landscape of variants in pre-mRNA-processing factor genes in an Irish cohort.Genet Med Open202642405195PubTator, text miningPubMed
The TOM Complex in the Outer Membrane of Mitochondria: A Supramolecular Assembly for Protein Import.Adv Exp Med Biol202642334539PubTator, text miningPubMed

1 to 10 of 1,640

See all 1,640 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/24148

GET https://conductscience.org/api/genes/v1/24148/patents?page=2