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IL27: interleukin 27

1 protein, 119 patents, 0 drugs, 0 trials, 3,579 NIH grants and 6,339 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL27HGNC
Nameinterleukin 27HGNC
NCBI Gene ID246778NCBI Gene
HGNC IDHGNC:19157HGNC
EnsemblENSG00000197272NCBI Gene
AliasesIL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8NEV9Interleukin-27 subunit alpha2434Ensembl, GeneID, HGNCUniProt

Patents 119

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026171886 A12026-08-207Q8NEV9Espacenet
EP 4791437 A12026-08-19174Q8NEV9Espacenet
EP 4757832 A12026-06-17443Q8NEV9Espacenet
JP 2026016604 A2026-02-03699Q8NEV9Espacenet
US 12534732 B22026-01-27916Q8NEV9Espacenet
JP 2026012378 A2026-01-23916Q8NEV9Espacenet
JP 2026502391 A2026-01-222Q8NEV9Espacenet
US 12516329 B22026-01-06916Q8NEV9Espacenet
EP 4670792 A22025-12-31916Q8NEV9Espacenet
WO 2025252853 A12025-12-111Q8NEV9Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3579

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01AI039671Costimulatory Mechanisms of Autoimmunity222,025NIH's project files
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases172,025NIH's project files
P30CA016672Cancer Center Support Grant152,025NIH's project files
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award142,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success112,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)92,025NIH's project files
P51OD011132Emory National Primate Research Center92,025NIH's project files
R01AR046713Cytokine regulation of RA synoviocyte phenotype92,025NIH's project files

Papers 6339

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42813654PubTator, text miningPubMed
42810907PubTator, text miningPubMed
42792776PubTator, text miningPubMed
42784468PubTator, text miningPubMed
42780496PubTator, text miningPubMed
42712571PubTator, text miningPubMed
42667461PubTator, text miningPubMed
42650831PubTator, text miningPubMed
42638975PubTator, text miningPubMed
42619935PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license