Gene · 248
ALPI: alkaline phosphatase, intestinal
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALPI: alkaline phosphatase, intestinal. Genes, record 248. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/248
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P09923 | Intestinal-type alkaline phosphatase | 528 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents89
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12648987 B2 | 2026-06-09 | 1 | P09923 | Espacenet |
| JP 2026516499 A | 2026-05-25 | 12 | P09923 | Espacenet |
| JP 2026516225 A | 2026-05-20 | 19 | P09923 | Espacenet |
| EP 4709762 A2 | 2026-03-18 | 12 | P09923 | Espacenet |
| EP 4704882 A2 | 2026-03-11 | 19 | P09923 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 37085 | P09923 | Espacenet |
| US 12508304 B2 | 2025-12-30 | 1 | P09923 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3619 | P09923 | Espacenet |
| US 12472147 B2 | 2025-11-18 | 1 | P09923 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3214 | P09923 | Espacenet |
1 to 10 of 89
See all 89 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,273
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALPI papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 10 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 9 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 9 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 9 | 2025 |
| P01HL131474 | Protein Glycosylation in the Coagulopathy and Inflammation of Sepsis | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| T32DK007754 | Research Training in Alimentary Tract Surgery | 6 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 5 | 2025 |
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,273Source NIH's project files
See all 1,273 nih grantsPapers2,303
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Non-genetic remodeling drives leukemia propagation and reveals actionable vulnerabilities in acute myeloid leukemia. | Cell Rep Med | 2026 | 42673946 | PubTator, text mining | PubMed |
| EnView: a tunable microphysiological platform with human crypt-scale topography and independent apical-basal flow for long-term culture and imaging of colonic epithelial monolayers. | Lab Chip | 2026 | 42614112 | PubTator, text mining | PubMed |
| Redefining biologically borderline resectable pancreatic cancer: a data-driven reassessment of CA19-9 cutoff and a preoperative lymph node metastasis prediction model. | Surg Today | 2026 | 42566027 | PubTator, text mining | PubMed |
| Linker attachment points: "finishing touch" in PROTAC design. | RSC Med Chem | 2026 | 42519712 | PubTator, text mining | PubMed |
| Integrative Proteomics and Phosphoproteomics Profiling of Chronic Enteropathy Associated with SLCO2A1 Gene Reveals Mucosal Barrier Impairment and Focal Adhesion Pathway Alterations. | Biomedicines | 2026 | 42511887 | PubTator, text mining | PubMed |
| Proteome-Wide Mendelian Randomization Identifies Causal Proteins for Multiple Sclerosis Susceptibility and Severity. | Genes (Basel) | 2026 | 42510850 | PubTator, text mining | PubMed |
| Exploring the Dynamic Interplay of Carbon Nanotubes with Apoptosis In-vitro and In-vivo: Insights from Bcl-2 and IAP Families. | Iran J Biotechnol | 2026 | 42473593 | PubTator, text mining | PubMed |
| SYNGR2 as a Multifaceted Biomarker in Hepatocellular Carcinoma Linking Prognosis, Immune Microenvironment and Therapeutic Response. | Technol Cancer Res Treat | 2026 | 42470438 | PubTator, text mining | PubMed |
| From charge shifting to membrane engagement: next-generation cubosomes for enhanced intracellular drug delivery. | Int J Pharm | 2026 | 42468653 | PubTator, text mining | PubMed |
| Co-exposure to polystyrene nanoparticles and tetrabromobisphenol A induces genotoxicity and interferes with intestinal barrier differentiation. | Cell Biol Toxicol | 2026 | 42432198 | PubTator, text mining | PubMed |
1 to 10 of 2,303
See all 2,303 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/248
GET https://conductscience.org/api/genes/v1/248/patents?page=2