Gene · 2492
FSHR: follicle stimulating hormone receptor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FSHR: follicle stimulating hormone receptor. Genes, record 2492. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2492
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P23945 | Follicle-stimulating hormone receptor | 695 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 46500 | P23945 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11846 | P23945 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12630 | P23945 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5566 | P23945 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 12630 | P23945 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11846 | P23945 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 5566 | P23945 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 5566 | P23945 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 5573 | P23945 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 32475 | P23945 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs7
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| CORIFOLLITROPIN ALFA | CHEMBL2108185 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
| FOLLITROPIN | CHEMBL4297955 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
| FOLLITROPIN ALFA | CHEMBL1201692 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
| FOLLITROPIN BETA | CHEMBL5315126 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
| FOLLITROPIN DELTA | CHEMBL5315064 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
| MENOTROPINS | CHEMBL2108427 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
| UROFOLLITROPIN | CHEMBL1201520 | Follicle stimulating hormone receptor agonist | AGONIST | ChEMBL |
Trials263
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07409493 | FOLLITROPIN | ClinicalTrials.gov | ||
| NCT07346235 | FOLLITROPIN | PHASE3 | ClinicalTrials.gov | |
| NCT07216742 | MENOTROPINS | PHASE3 | ClinicalTrials.gov | |
| NCT07153367 | FOLLITROPIN DELTA | PHASE2 | ClinicalTrials.gov | |
| NCT07148999 | MENOTROPINS | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT07128394 | FOLLITROPIN | ClinicalTrials.gov | ||
| NCT06997900 | MENOTROPINS | PHASE2 | ClinicalTrials.gov | |
| NCT06997900 | FOLLITROPIN DELTA | PHASE2 | ClinicalTrials.gov | |
| NCT06803199 | FOLLITROPIN | ClinicalTrials.gov | ||
| NCT06635538 | CORIFOLLITROPIN ALFA | ClinicalTrials.gov |
1 to 10 of 263
See all 263 trialsNIH grants1,110
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FSHR papers | Newest fiscal year |
|---|---|---|---|
| P01AG029531 | The Aging Pituitary/Gonadal Axis | 26 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 11 | 2025 |
| U19AG060917 | FSH - an Aging Hormone? | 9 | 2025 |
| P20GM103418 | Kansas IDeA Network of Biomedical Research Excellence 5 | 6 | 2025 |
| R01AG071870 | Proof-of-Concept and Mechanistic Studies to Repurpose Erectile Dysfunction Drugs for Elderly Females | 6 | 2025 |
| R01AG074092 | Elevated FSH - A Driver for Sex Differences in Alzheimer's Disease | 6 | 2025 |
| U01AG073148 | A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's Disease | 6 | 2025 |
| K12HD000849 | Reproductive Scientist Development Program | 5 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 5 | 2025 |
| R01HL016037 | Molecular Regulation of Cardiovascular 7 TM Receptors | 5 | 2025 |
1 to 10 of 1,110Source NIH's project files
See all 1,110 nih grantsPapers3,947
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Spatiotemporal modeling of GPCR signaling: The role of endosomal dynamics and receptor recycling. | PLoS Comput Biol | 2026 | 42809610 | PubTator, text mining | PubMed |
| Gonadotropin-resistant ovary syndrome in a hypergonadotropic patient with FSHR/FSHB polymorphisms and abnormal karyotype. | JCEM Case Rep | 2026 | 42751053 | PubTator, text mining | PubMed |
| Co-exposure to high temperature and mono(2-ethylhexyl) phthalate inhibits mouse antral follicle growth and estradiol synthesis: phthalate-heat interactions in the ovary. | Toxicol Sci | 2026 | 42745480 | PubTator, text mining | PubMed |
| Phenotype-Specific Association of LHCGR rs13405728 Polymorphism with Anovulatory Infertility in Malay Women with Polycystic Ovary Syndrome: A Case-Control Study. | Int J Fertil Steril | 2026 | 42703834 | PubTator, text mining | PubMed |
| Optimisation of Dietary Lipid in Genetically Selected Clarias magur in Term of Gonadal Growth, Reproductive Performance, and Expression of Reproduction-Related Genes. | J Anim Physiol Anim Nutr (Berl) | 2026 | 42641055 | PubTator, text mining | PubMed |
| Epigenetic regulation of ovarian steroidogenesis in PCOS: HDAC inhibitors and short-chain fatty acids. | Mol Biol Rep | 2026 | 42627443 | PubTator, text mining | PubMed |
| Single-cell atlas of reproductive endocrine organs reveals transcriptomic responses to type 1 diabetes mellitus in nonhuman primates. | Cell Discov | 2026 | 42552301 | PubTator, text mining | PubMed |
| Polycystic ovary syndrome and insulin resistance: A focus on pathogenesis, risk factors, and therapeutic strategies. | J Reprod Immunol | 2026 | 42531755 | PubTator, text mining | PubMed |
| Network toxicology based research into the effect and mechanism of plasticizers on infertility. | Front Pharmacol | 2026 | 42523946 | PubTator, text mining | PubMed |
| Scutellarin Alleviates Zearalenone-Induced Injury in Porcine Ovarian Granulosa Cells Through WNT5A-Associated Regulation of Cell-Cycle-Related Proteins. | Vet Sci | 2026 | 42514729 | PubTator, text mining | PubMed |
1 to 10 of 3,947
See all 3,947 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2492
GET https://conductscience.org/api/genes/v1/2492/patents?page=2