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ALPP: alkaline phosphatase, placental

1 protein, 85 patents, 0 drugs, 0 trials, 4,803 NIH grants and 40,515 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolALPPHGNC
Namealkaline phosphatase, placentalHGNC
NCBI Gene ID250NCBI Gene
HGNC IDHGNC:439HGNC
EnsemblENSG00000163283NCBI Gene
AliasesALP, PALP, PLAP, PLAP-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05187Alkaline phosphatase, placental type5358Ensembl, GeneID, HGNCUniProt

Patents 85

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026156020 A22026-07-23379P05187Espacenet
WO 2026156021 A12026-07-23379P05187Espacenet
JP 2026516225 A2026-05-2017P05187Espacenet
EP 4704882 A22026-03-1117P05187Espacenet
JP 2026004568 A2026-01-1437093P05187Espacenet
JP 2025542294 A2025-12-25275P05187Espacenet
EP 4650780 A22025-11-1910884P05187Espacenet
JP 2025147176 A2025-10-06758P05187Espacenet
JP 2025529142 A2025-09-045458P05187Espacenet
US 12371689 B22025-07-295458P05187Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4803

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01CA142746Subcellular enzyme-instructed self-assembly for molecular anticancer nanomedicines732,025NIH's project files
P30CA008748Cancer Center Support Grant442,025NIH's project files
P30CA016672Cancer Center Support Grant302,025NIH's project files
ZICBC010685Postmortem Pathology222,025NIH's project files
UC7AI094660Limited Competition: National Biocontainment Laboratories (NBLs) Operations Support (UC7 Clinical Trial Not Allowed)212,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award212,025NIH's project files
U01DK065201University of North Carolina Clinical Center for DILIN182,025NIH's project files
U01DK065184Michigan Hepatotoxicity Clinical Research Network Renewal172,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease162,025NIH's project files
U01DK065176Drug Induced Liver Injury Network Data Coordinating Center162,025NIH's project files

Papers 40515

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825391PubTator, text miningPubMed
42821325PubTator, text miningPubMed
42815331PubTator, text miningPubMed
42814851PubTator, text miningPubMed
42813526PubTator, text miningPubMed
42812814PubTator, text miningPubMed
42810859PubTator, text miningPubMed
42808805PubTator, text miningPubMed
42807297PubTator, text miningPubMed
42807128PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license