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Gene · 2512

FTL: ferritin light chain

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FTL: ferritin light chain. Genes, record 2512. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2512

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Gene

Symbol
FTL
HGNC
Name
ferritin light chain
HGNC
NCBI Gene ID
2512
NCBI Gene
HGNC ID
HGNC:3999
HGNC
Ensembl
ENSG00000087086
NCBI Gene
Aliases
FTL1, LFTD, MGC71996, NBIA3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P02792Ferritin light chain17517Ensembl, GeneID, HGNC

Source UniProt

Patents103

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446183P02792Espacenet
WO 2025248034 A12025-12-0414P02792Espacenet
EP 4656659 A12025-12-0314P02792Espacenet
EP 4641202 A22025-10-295675P02792Espacenet
JP 2025081326 A2025-05-2742P02792Espacenet
WO 2025081160 A12025-04-1768P02792Espacenet
JP 2025032204 A2025-03-1128641P02792Espacenet
KR 1020250017231 A2025-02-045675P02792Espacenet
EP 4461818 A22024-11-1328641P02792Espacenet
EP 4406544 A22024-07-3113P02792Espacenet

1 to 10 of 103

See all 103 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,436

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFTL papersNewest fiscal year
P30ES006694Southwest Environmental Health Sciences Center72025
P30CA008748Cancer Center Support Grant52025
P30CA091842Cancer Center Support Grant52025
P42ES004940The DUST Center: Hazardous Dust in Drylands - Exposure, Health Impacts, and Mitigation52025
P30CA016087Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30CA062203Cancer Center Support Grant42025
P30CA086862Cancer Center Support Grant42025
UL1TR001863Yale Clinical and Translational Science Award42025
ZIAEY000281Clinical/molecular Studies In Families With Congenital Or Hereditary Cataracts42025

1 to 10 of 1,436Source NIH's project files

See all 1,436 nih grants

Papers2,666

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
rsRNA-28S-21 promotes endometrial cancer by regulating ferroptosis through the NSUN5-FTH1/FTL pathway.Gene202642826770PubTator, text miningPubMed
Artesunate alleviates cisplatin-induced nephrotoxicity by regulating tryptophan metabolism and inhibiting ferroptosis.Front Pharmacol202642807112PubTator, text miningPubMed
NRF2-Regulated Ferroptosis in Breast Cancer: Mechanisms, Resistance, and Therapeutic Opportunities.Asia Pac J Clin Oncol202642802387PubTator, text miningPubMed
Solasonine inhibits growth of gastric cancer by targeting FTL-mediated ferroptosis.Bioorg Chem202642777387PubTator, text miningPubMed
Exploratory single-nucleus transcriptomic analysis of endothelial heterogeneity and ferroptosis-related gene patterns in a human hepatocellular carcinoma sample.Transl Oncol202642759407PubTator, text miningPubMed
The emerging landscape of polymerase θ in tumor pathogenesis and precision treatment.Biochem Biophys Res Commun202642748573PubTator, text miningPubMed
Predicting diagnostic gene biomarkers associated with immune infiltration in patients with diabetes.Braz J Med Biol Res202642715469PubTator, text miningPubMed
Single-Cell Transcriptomics of Pyrimidine Salvage in HBV-Related HCC Reveals Prognostic and Immune Infiltration Features.Biomol Ther (Seoul)202642676041PubTator, text miningPubMed
Cross-cancer transcriptomic analysis reveals conserved developmental, ferroptosis, and immune remodeling modules in Wilms tumor and oral cancer.Front Genet202642670482PubTator, text miningPubMed
Iron Dyshomeostasis and Divergent Antigen Presentation Remodeling in Bronchiectasis: A Dual-Dataset Transcriptomic Analysis.J Inflamm Res202642670432PubTator, text miningPubMed

1 to 10 of 2,666

See all 2,666 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2512

GET https://conductscience.org/api/genes/v1/2512/patents?page=2