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Gene · 2525

FUT3: fucosyltransferase 3 (Lewis blood group)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FUT3: fucosyltransferase 3 (Lewis blood group). Genes, record 2525. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2525

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Gene

Symbol
FUT3
HGNC
Name
fucosyltransferase 3 (Lewis blood group)
HGNC
NCBI Gene ID
2525
NCBI Gene
HGNC ID
HGNC:4014
HGNC
Ensembl
ENSG00000171124
NCBI Gene
Aliases
CD174, FT3B, FucT-III, LE, Les
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P212173-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT33610Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446742P21217Espacenet
JP 2026004568 A2026-01-1446743P21217Espacenet
JP 2026004568 A2026-01-1446744P21217Espacenet
JP 2026004568 A2026-01-1446745P21217Espacenet
EP 4640849 A22025-10-29574P21217Espacenet
EP 4641201 A22025-10-293901P21217Espacenet
JP 2025519096 A2025-06-24574P21217Espacenet
JP 2025517969 A2025-06-123901P21217Espacenet
US 11446398 B22022-09-2032998P21217Espacenet
US 11446398 B22022-09-2032999P21217Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants640

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFUT3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant52025
U01CA210170Using markers to improve pancreatic cancer screening and surveillance: a multi-center study42025
P30CA016672Cancer Center Support Grant32025
P30DK056338Texas Medical Center Digestive Diseases Center32025
R01AI036040STRUCTURAL STUDIES ON ROTAVIRUS32025
R01AI080656Regulation of Rotavirus Replication32025
K24AI141744Understanding protection against norovirus at the maternal-child interface22025
P20GM125498Translational Global Infectious Diseases Research Center22025
P30CA010815Consolidated Basic Cancer Research Program22025
P30CA068485Cancer Center Support Grant22025

1 to 10 of 640Source NIH's project files

See all 640 nih grants

Papers1,387

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CLDN18 as a novel junctional biomarker enhancing multi-gene classification of pancreatic cancer.Transl Oncol202642691511PubTator, text miningPubMed
Genetically determined ABO blood group, secretor status, Lewis antigens, and panNEN risk.Endocr Relat Cancer202642659511PubTator, text miningPubMed
Lewis antigen and antibody testing as practical first-line approaches for detecting CA19-9 non-producers.Transfus Apher Sci202642302476PubTator, text miningPubMed
FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3-Mediated ErbB3 Fucosylation in Lung Adenocarcinoma.Adv Sci (Weinh)202642299774PubTator, text miningPubMed
Early postoperative carbohydrate antigen 19-9 normalization drives prognosis after pancreatic ductal adenocarcinoma resection.J Gastrointest Surg202642173352PubTator, text miningPubMed
A New CA19-9 Cutoff Value Identifies Lewis Antigen Status and Refines Prognostic Stratification in PDAC.Clin Cancer Res202642162970PubTator, text miningPubMed
Lewis blood group genetic and phenotypic diversity in a Thai population.Transfus Apher Sci202642119257PubTator, text miningPubMed
Decoding the HMO‒microbiome axis: bridging maternal milk to infant health outcomes.Gut Microbes202641888026PubTator, text miningPubMed
Prognostic Value of Combined Carbohydrate Antigen 19-9 and Duke Pancreatic Monoclonal Antigen Type 2 Assessment in Biliary Tract Cancer.Ann Surg Oncol202641886033PubTator, text miningPubMed
A Sequential Proteomic Relay Defines a Decade-long Pre-diagnostic Window for Pancreatic Cancer.Cancer Diagn Progn202641778239PubTator, text miningPubMed

1 to 10 of 1,387

See all 1,387 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2525

GET https://conductscience.org/api/genes/v1/2525/patents?page=2