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Gene · 2532

ACKR1: atypical chemokine receptor 1 (Duffy blood group)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACKR1: atypical chemokine receptor 1 (Duffy blood group). Genes, record 2532. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2532

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Gene

Symbol
ACKR1
HGNC
Name
atypical chemokine receptor 1 (Duffy blood group)
HGNC
NCBI Gene ID
2532
NCBI Gene
HGNC ID
HGNC:4035
HGNC
Ensembl
ENSG00000213088
NCBI Gene
Aliases
CCBP1, CD234, DARC, DARC/ACKR1, Dfy, FY, GPD, GpFy, WBCQ1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16570Atypical chemokine receptor 13366Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444371Q16570Espacenet
JP 2026004568 A2026-01-1444373Q16570Espacenet
JP 2026004568 A2026-01-1444375Q16570Espacenet
JP 2025147176 A2025-10-0616716Q16570Espacenet
JP 2025529142 A2025-09-04232Q16570Espacenet
US 12371689 B22025-07-29232Q16570Espacenet
JP 2025062604 A2025-04-147878Q16570Espacenet
JP 2025062604 A2025-04-147880Q16570Espacenet
JP 2025028160 A2025-02-2816716Q16570Espacenet
KR 1020250010750 A2025-01-2116716Q16570Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,590

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACKR1 papersNewest fiscal year
P30EY001792P30 Core Grant for Vision Research152025
P30AI045008Penn Center for AIDS Research102025
P30CA068485Cancer Center Support Grant92025
R01AI139618Nucleoside-modified mRNA vaccine for prevention and treatment of genital herpes92025
R01EY019896Developing A Tissue-Targeted Ocular HSV Therapeutic Vaccine72025
UL1TR001863Yale Clinical and Translational Science Award72025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success72025
ZIAAI000548Development Of Vaccines For Genital Herpes Simplex Infection72025
P30CA008748Cancer Center Support Grant62025
R01EY024710A new molecular therapy against ocular herpes62025

1 to 10 of 2,590Source NIH's project files

See all 2,590 nih grants

Papers3,550

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Tumor Vascular Features and Colorectal Cancer-Specific Mortality.JAMA Netw Open202642804694PubTator, text miningPubMed
Malaria-Related Host Genetic Variation in an Endemic Population of Southern Senegal.Int J Mol Sci202642794552PubTator, text miningPubMed
Atypical Chemokine Receptor DARC/ACKR1 Is Expressed Selectively by Neurons with Regional Heterogeneity and Protects against Neuroinflammation and Cognitive Impairment.bioRxiv202642779766PubTator, text miningPubMed
Blood Cell Counts and the Duffy Null Phenotype: Beyond Neutropenia.Int J Lab Hematol202642678004PubTator, text miningPubMed
LATS1/2 inactivation drives a distinct venous endothelial cell response that contributes to fibrotic remodeling of the lung.Sci Adv202642664350PubTator, text miningPubMed
A CHO-Expressed Pseudorabies Virus gD Subunit Vaccine Elicits Potent Neutralizing Antibodies and Confers Complete Protection Against Lethal Challenge in Mice.Vaccines (Basel)202642646727PubTator, text miningPubMed
Antiviral activity of biogenic silver nanoparticles against HSV-1: integrating computational modeling and experimental validation.Iran J Microbiol202642626032PubTator, text miningPubMed
ACKR1-expressing venous endothelial cells establish a pro-fibrotic niche in pulmonary fibrosis.bioRxiv202642620057PubTator, text miningPubMed
Enhanced salivary correlation between Streptococcus mutans and herpes simplex virus-1 in oral squamous cell carcinoma: a case-control study.BMC Oral Health202642601617PubTator, text miningPubMed
Topical Glycolysis Inhibition Restores MAVS-Associated Antiviral Signaling in Herpes Simplex Keratitis.Invest Ophthalmol Vis Sci202642530913PubTator, text miningPubMed

1 to 10 of 3,550

See all 3,550 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2532

GET https://conductscience.org/api/genes/v1/2532/patents?page=2