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RICTOR: RPTOR independent companion of MTOR complex 2

1 protein, 20 patents, 0 drugs, 0 trials, 3,358 NIH grants and 5,053 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRICTORHGNC
NameRPTOR independent companion of MTOR complex 2HGNC
NCBI Gene ID253260NCBI Gene
HGNC IDHGNC:28611HGNC
EnsemblENSG00000164327NCBI Gene
AliasesAVO3, KIAA1999, MGC39830, PIA, hAVO3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q6R327Rapamycin-insensitive companion of mTOR1,70816Ensembl, GeneID, HGNCUniProt

Patents 20

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-297386Q6R327Espacenet
JP 2025517969 A2025-06-127386Q6R327Espacenet
US 11564998 B22023-01-315929Q6R327Espacenet
JP 2022141755 A2022-09-29542Q6R327Espacenet
US 11446398 B22022-09-2076047Q6R327Espacenet
JP 2022524081 A2022-04-27179018Q6R327Espacenet
US 10463751 B22019-11-055929Q6R327Espacenet
JP 2018023373 A2018-02-1528656Q6R327Espacenet
US 9572897 B22017-02-215929Q6R327Espacenet
JP 2016519285 A2016-06-30542Q6R327Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3358

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant652,025NIH's project files
P30CA008748Cancer Center Support Grant362,025NIH's project files
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes292,025NIH's project files
P30CA068485Cancer Center Support Grant142,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center132,025NIH's project files
P30CA006973Regional Oncology Research Center102,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant102,025NIH's project files
P30DK026743UCSF Liver Center102,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)92,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA92,025NIH's project files

Papers 5053

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817668PubTator, text miningPubMed
42808379PubTator, text miningPubMed
42782481PubTator, text miningPubMed
42727655PubTator, text miningPubMed
42682084PubTator, text miningPubMed
42648032PubTator, text miningPubMed
42626765PubTator, text miningPubMed
42583078PubTator, text miningPubMed
42510705PubTator, text miningPubMed
42503352PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license