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G6PC1: glucose-6-phosphatase catalytic subunit 1

1 protein, 63 patents, 0 drugs, 0 trials, 2,574 NIH grants and 8,800 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolG6PC1HGNC
Nameglucose-6-phosphatase catalytic subunit 1HGNC
NCBI Gene ID2538NCBI Gene
HGNC IDHGNC:4056HGNC
EnsemblENSG00000131482NCBI Gene
AliasesG6PC, G6PT, G6Pase, GSD1, GSD1aNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35575Glucose-6-phosphatase catalytic subunit 13576Ensembl, GeneID, HGNCUniProt

Patents 63

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21113P35575Espacenet
JP 2025169942 A2025-11-141013P35575Espacenet
EP 4640849 A22025-10-29174P35575Espacenet
EP 4641201 A22025-10-291086P35575Espacenet
US 12440580 B22025-10-142P35575Espacenet
JP 2025529142 A2025-09-041647P35575Espacenet
JP 2025525390 A2025-08-053659P35575Espacenet
US 12371689 B22025-07-291647P35575Espacenet
JP 2025519096 A2025-06-24174P35575Espacenet
JP 2025517969 A2025-06-121086P35575Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2574

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAHD000912Molecular Genetics Of Heritable Human Disorders712,025NIH's project files
T32DK007563Multidisciplinary Training in Molecular Endocrinology262,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)222,025NIH's project files
P30CA068485Cancer Center Support Grant162,025NIH's project files
P30DK020593Vanderbilt Diabetes Research Center152,025NIH's project files
P30DK019525University of Pennsylvania Diabetes Research Center112,025NIH's project files
P30DK045735Yale Diabetes Research Center102,025NIH's project files
P30CA008748Cancer Center Support Grant82,025NIH's project files
P30CA013330Cancer Center Support Grant82,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)82,025NIH's project files

Papers 8800

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826778PubTator, text miningPubMed
42790170PubTator, text miningPubMed
42720574PubTator, text miningPubMed
42674977PubTator, text miningPubMed
42641853PubTator, text miningPubMed
42619769PubTator, text miningPubMed
42619682PubTator, text miningPubMed
42617994PubTator, text miningPubMed
42587331PubTator, text miningPubMed
42583078PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license