Gene · 253943
YTHDF3: YTH N6-methyladenosine RNA binding protein F3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. YTHDF3: YTH N6-methyladenosine RNA binding protein F3. Genes, record 253943. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/253943
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q7Z739 | YTH domain-containing family protein 3 | 585 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents10
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 18057 | Q7Z739 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 22426 | Q7Z739 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 22426 | Q7Z739 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 18057 | Q7Z739 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 810 | Q7Z739 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 98272 | Q7Z739 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 201243 | Q7Z739 | Espacenet |
| EP 3504344 A1 | 2019-07-03 | 999 | Q7Z739 | Espacenet |
| JP 2005006658 A | 2005-01-13 | 2908 | Q7Z739 | Espacenet |
| EP 1447413 A2 | 2004-08-18 | 2865 | Q7Z739 | Espacenet |
Drugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants632
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | YTHDF3 papers | Newest fiscal year |
|---|---|---|---|
| RM1HG008935 | Center for dynamic RNA epitranscriptomes - Renewal | 13 | 2025 |
| R01CA186702 | Mechanisms of epitranscriptomic regulation in cancer | 9 | 2025 |
| P30AI064518 | Center for AIDS Research | 5 | 2025 |
| R01AI125416 | Defining the role of the RNA modification N6-methyladenosine during Flaviviridae virus infection | 5 | 2025 |
| R35NS111631 | New mechanisms and technologies for understanding post-transcriptional gene regulation in neurons | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| R01GM056927 | Control of Translation in Herpesvirus Infected Cells - Resubmission - 1 | 4 | 2025 |
| T32AI007647 | Training Program in Mechanisms of Virus-Host Interactions | 4 | 2025 |
| P20GM103436 | IDeA Networks of Biomedical Research Excellence in Kentucky | 3 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 632Source NIH's project files
See all 632 nih grantsPapers2,249
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Single residues within the YTHDF intrinsically disordered region control m 6 A-dependent mRNA decay. | bioRxiv | 2026 | 42818126 | PubTator, text mining | PubMed |
| YTHDF3 promotes angiogenesis in endometriosis by enhancing the translation efficiency of PFKFB3. | Angiogenesis | 2026 | 42776305 | PubTator, text mining | PubMed |
| YTHDF3 Promoted Gastric Cancer Progression by Facilitating m6A-Dependent Degradation of APC mRNA. | Anal Cell Pathol (Amst) | 2026 | 42742540 | PubTator, text mining | PubMed |
| RNA m⁶A modification and its regulatory factors are altered in granulosa cells from women with PMOS. | J Assist Reprod Genet | 2026 | 42687053 | PubTator, text mining | PubMed |
| Comprehensive Analysis of m6A Regulators Identifies YTHDF3 as a Promising Prognostic Biomarker for Breast Cancer. | J Vis Exp | 2026 | 42612048 | PubTator, text mining | PubMed |
| Ythdf family m6A readers promote retinal ganglion cell fate reprogramming and neurite development. | Exp Eye Res | 2026 | 42595204 | PubTator, text mining | PubMed |
| YTHDF3 Promotes the Progression of Gastric Cancer by Activating the Wnt/β-Catenin Signaling Pathway via Targeting NEK7. | J Gastroenterol Hepatol | 2026 | 42533606 | PubTator, text mining | PubMed |
| p53 hotspot mutants attenuate CTL-mediated tumor cell killing through a novel ALKBH5-YTHDF3-PD-L1 pathway. | Oncogene | 2026 | 42533115 | PubTator, text mining | PubMed |
| RGS16 Aggravates Hepatic Ischemia-Reperfusion Injury via Hepatocyte-Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis. | Adv Sci (Weinh) | 2026 | 42517511 | PubTator, text mining | PubMed |
Correction: Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3. | Mol Cancer | 2026 | 42436539 | PubTator, text mining | PubMed |
1 to 10 of 2,249
See all 2,249 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/253943
GET https://conductscience.org/api/genes/v1/253943/grants?page=2