Gene · 2549
GAB1: GRB2 associated binding protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GAB1: GRB2 associated binding protein 1. Genes, record 2549. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2549
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13480 | GRB2-associated-binding protein 1 | 694 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents19
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48230 | Q13480 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1720 | Q13480 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1720 | Q13480 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 28661 | Q13480 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 28661 | Q13480 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 28661 | Q13480 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 36290 | Q13480 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 139261 | Q13480 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 4269 | Q13480 | Espacenet |
| US 10677795 B2 | 2020-06-09 | 767 | Q13480 | Espacenet |
1 to 10 of 19
See all 19 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,656
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GAB1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 23 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 17 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 10 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 9 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 7 | 2025 |
| R01CA069202 | Structure/Function of Protein Tyrosine Phosphatases | 5 | 2025 |
| R01CA159859 | Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma | 5 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
1 to 10 of 1,656Source NIH's project files
See all 1,656 nih grantsPapers2,374
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Comparative Evaluation of Immunohistochemistry With DNA Methylation Profiling for Molecular Classification of Medulloblastomas: A Single-Institution Cohort Study. | Appl Immunohistochem Mol Morphol | 2026 | 42813612 | PubTator, text mining | PubMed |
| Integrative genomic and single-cell transcriptomic analyses suggest a putative zinc transport-immune axis in Meniere's disease. | Front Neurol | 2026 | 42775259 | PubTator, text mining | PubMed |
| Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival. | Brain Pathol | 2026 | 42707049 | PubTator, text mining | PubMed |
| Inherent α-Helix Around Tyrosine 183 in the Intrinsically Disordered Tail of the Multi-Site Docking Platform Gab1. | Biopolymers | 2026 | 42549985 | PubTator, text mining | PubMed |
| Targeting the adaptor protein Gab1 overcomes MET/Src-driven alectinib resistance in ALK-rearranged NSCLC. | Cell Signal | 2026 | 42492818 | PubTator, text mining | PubMed |
| Identification of Markers on the Basis of Transcriptomic Analysis for Molecular Assignment of Medulloblastoma. | Int J Mol Sci | 2026 | 42449993 | PubTator, text mining | PubMed |
| Uncovering functional variants using a high-efficiency PE3-based screening platform. | Sci Adv | 2026 | 42247518 | PubTator, text mining | PubMed |
| Integrative circRNA landscape of intrauterine adhesions: putative ceRNA axes and circRNA-associated splicing usage linked to contractility and immunity. | Front Mol Biosci | 2026 | 42181770 | PubTator, text mining | PubMed |
| PI3K Regulates Wild-type RAS Signaling to Confer Resistance to KRAS Inhibition. | Cancer Res | 2026 | 42095550 | PubTator, text mining | PubMed |
| Gαi1 and Gαi3 mediate IL-11-induced signal transduction and are potential therapeutic targets for LUAD. | Cell Death Dis | 2026 | 42034606 | PubTator, text mining | PubMed |
1 to 10 of 2,374
See all 2,374 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2549
GET https://conductscience.org/api/genes/v1/2549/patents