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Gene · 2551

GABPA: GA binding protein transcription factor subunit alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GABPA: GA binding protein transcription factor subunit alpha. Genes, record 2551. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2551

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Gene

Symbol
GABPA
HGNC
Name
GA binding protein transcription factor subunit alpha
HGNC
NCBI Gene ID
2551
NCBI Gene
HGNC ID
HGNC:4071
HGNC
Ensembl
ENSG00000154727
NCBI Gene
Aliases
E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q06546GA-binding protein alpha chain4540Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4805517 A12026-09-1619Q06546Espacenet
JP 2026004568 A2026-01-1447153Q06546Espacenet
JP 2026004568 A2026-01-1447154Q06546Espacenet
EP 4650780 A22025-11-197100Q06546Espacenet
JP 2025147176 A2025-10-0615024Q06546Espacenet
JP 2025517970 A2025-06-127100Q06546Espacenet
JP 2025028160 A2025-02-2815024Q06546Espacenet
KR 1020250010750 A2025-01-2115024Q06546Espacenet
JP 2024109657 A2024-08-1414863Q06546Espacenet
KR 1020240010752 A2024-01-24181Q06546Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,232

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGABPA papersNewest fiscal year
P30CA042014Cancer Center Support Grant72025
P01CA118816Imaging and Genomic Signatures of Brain Tumor Heterogeneity and Evolution to Optimize Patient Management62025
P50CA097257Brain Tumor SPORE Grant62025
P20GM103427Nebraska Research Network in Functional Genomics52025
P30CA008748Cancer Center Support Grant52025
R01ES025748Activation of Nrf2 during embryonic development - mechanisms and consequences52025
R01CA163336Predicting Transcriptional and Epigenetic Networks in Cancer from Sequencing Data42025
P20GM103423The Maine Biomedical Research Network (INBRE)32025
P30CA045508CSHL Cancer Center Support Grant32025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025

1 to 10 of 1,232Source NIH's project files

See all 1,232 nih grants

Papers1,402

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The IKKε-GABPA axis regulates STING transcription to orchestrate antiviral immunity and inflammation.J Exp Med202642820930PubTator, text miningPubMed
A de novo GABPA Variant in a Patient with Multifocal Cutaneous Vascular Tumors of an Unclassified Entity.bioRxiv202642818108PubTator, text miningPubMed
Epigenetic training licenses naïve CD8+ T cell metabolic fitness and function.Sci Adv202642758848PubTator, text miningPubMed
scRNA-Seq Links CD8 Effector T Cells to Periodontitis via Transcriptional Reprogramming and Enhanced PARs Signaling.Oral Dis202642638197PubTator, text miningPubMed
Exposure to environmentally relevant concentrations of zearalenone disrupts blood-testis barrier via inositol-requiring enzyme 1α-dependent GA binding protein transcription factor α mRNA decay.Chem Biol Interact202642551538PubTator, text miningPubMed
Investigating the Role of Oxidative Stress Parameters in the Spectrum of Preschool Anxiety Disorders.Early Interv Psychiatry202642527997PubTator, text miningPubMed
Phosphorylated DEK sustains leukemia stem cells by enabling PBX3-driven transcriptional reprogramming.Blood202642378254PubTator, text miningPubMed
The Reconstitution of the Macrophage Niche Reveals Dynamic Transcriptional and Renal Macrophage-Epithelial Communication Networks.Cells202642346129PubTator, text miningPubMed
DDX21 Links BRAFV600E and TERT to Promote Thyroid Cancer Progression.Thyroid202641817108PubTator, text miningPubMed
Fibroblast-like Synoviocytes as Key Regulators of Homeostasis and Inflammation in the Joint Microenvironment of Inflammatory Arthritis.Biomedicines202641751295PubTator, text miningPubMed

1 to 10 of 1,402

See all 1,402 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2551

GET https://conductscience.org/api/genes/v1/2551/patents?page=2