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Gene · 2565

GABRG1: gamma-aminobutyric acid type A receptor subunit gamma1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GABRG1: gamma-aminobutyric acid type A receptor subunit gamma1. Genes, record 2565. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2565

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Gene

Symbol
GABRG1
HGNC
Name
gamma-aminobutyric acid type A receptor subunit gamma1
HGNC
NCBI Gene ID
2565
NCBI Gene
HGNC ID
HGNC:4086
HGNC
Ensembl
ENSG00000163285
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8N1C3Gamma-aminobutyric acid receptor subunit gamma-14650Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447265Q8N1C3Espacenet
EP 4650780 A22025-11-193616Q8N1C3Espacenet
EP 4641201 A22025-10-293212Q8N1C3Espacenet
JP 2025529142 A2025-09-041663Q8N1C3Espacenet
US 12371689 B22025-07-291663Q8N1C3Espacenet
JP 2025517969 A2025-06-123212Q8N1C3Espacenet
JP 2025517970 A2025-06-123616Q8N1C3Espacenet
EP 4551941 A22025-05-1412Q8N1C3Espacenet
US 11446398 B22022-09-2033944Q8N1C3Espacenet
US 11400116 B22022-08-026354Q8N1C3Espacenet

1 to 10 of 30

See all 30 patents

Drugs76

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABP-700CHEMBL4297255GABA-A receptor; anion channel agonistAGONISTChEMBL
ACAMPROSATECHEMBL1201293GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ACAMPROSATE CALCIUMCHEMBL2068724GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ADIPIPLONCHEMBL2103791GABA-A receptor; anion channel partial agonistPARTIAL AGONISTChEMBL
ALPRAZOLAMCHEMBL661GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BREXANOLONECHEMBL207538GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITALCHEMBL449GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITAL SODIUMCHEMBL1200982GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTALBITALCHEMBL454GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
CENOBAMATECHEMBL3989949GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL

1 to 10 of 76

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Trials1,164

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants658

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGABRG1 papersNewest fiscal year
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).202025
P60AA007611Center on Genetic Determinants of Alcohol Ingestion and Responses to Alcohol52025
R28AA012725Brain Tissue Resource Center for Alcohol Research52025
ZIAAA000301Integrative genetics of behavior with high throughput technologies52025
P50AA012870Center for the Translational Neuroscience of Alcoholism32025
P60AA006420CNS Effects of Alcohol: Cellular Neurobiology32025
P30ES019776HERCULES: Exposome Research Center22025
P60AA010760Behavioral Genomics of Alcohol Neuroadaptation22025
R01AA012404Gene Expression in the Human Alcoholic Brain22025
R25MH077823Research Education for Future Physician-Scientists in Child Psychiatry22025

1 to 10 of 658Source NIH's project files

See all 658 nih grants

Papers347

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated bulk and single-cell RNA sequencing reveals a prognostic neuro-mimicry signature in papillary thyroid carcinoma.Discov Oncol202642329337PubTator, text miningPubMed
Loss of SALL1 Promotes Hepatocellular Carcinoma Growth and Is Associated with Poor Clinical Outcome.Cancers (Basel)202642122151PubTator, text miningPubMed
Multi-omics and electrophysiological examination of GABAA receptors in the dorsolateral prefrontal cortex of humans with alcohol use disorder.Mol Psychiatry202641965895PubTator, text miningPubMed
Integrated Clinical Genetic Analysis Reveals Transcriptional Neurotransmitter Receptor Dysregulation in Meningiomas Causing Seizure.Neurosurgery202641677355PubTator, text miningPubMed
Neuro-related gene signatures predict prognosis in diffuse large B-Cell lymphoma and uncover TRPV2-mediated tumor microenvironment regulation.Ann Hematol202641549103PubTator, text miningPubMed
Decoding the pituitary response to photoperiod in geese: Central role in regulating reproduction.Theriogenology202641420901PubTator, text miningPubMed
NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors.Elife202540875449PubTator, text miningPubMed
Differential Expression of GABA Receptor-Related Genes in Alzheimer's Disease and the Positive Regulatory Role of Aerobic Exercise-From Genetic Screening to D-gal-induced AD-like Pathology Model.Neuromolecular Med202439752101PubTator, text miningPubMed
Huanglian Jiedu decoction alleviates ischemia-induced cerebral injury in rats by mitigating NET formation and activiting GABAergic synapses.J Cell Mol Med202439099086PubTator, text miningPubMed
Gene Expression of GABAA Receptor Subunits and Association with Patient Survival in Glioma.Brain Sci202438539663PubTator, text miningPubMed

1 to 10 of 347

See all 347 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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