Gene · 2567
GABRG3: gamma-aminobutyric acid type A receptor subunit gamma3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GABRG3: gamma-aminobutyric acid type A receptor subunit gamma3. Genes, record 2567. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2567
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | 467 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 47270 | Q99928 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 18386 | Q99928 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 22874 | Q99928 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5696 | Q99928 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1665 | Q99928 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6442 | Q99928 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1665 | Q99928 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6442 | Q99928 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 22874 | Q99928 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 18386 | Q99928 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs76
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ABP-700 | CHEMBL4297255 | GABA-A receptor; anion channel agonist | AGONIST | ChEMBL |
| ACAMPROSATE | CHEMBL1201293 | GABA-A receptor; anion channel positive modulator | POSITIVE MODULATOR | ChEMBL |
| ACAMPROSATE CALCIUM | CHEMBL2068724 | GABA-A receptor; anion channel positive modulator | POSITIVE MODULATOR | ChEMBL |
| ADIPIPLON | CHEMBL2103791 | GABA-A receptor; anion channel partial agonist | PARTIAL AGONIST | ChEMBL |
| ALPRAZOLAM | CHEMBL661 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BREXANOLONE | CHEMBL207538 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BUTABARBITAL | CHEMBL449 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BUTABARBITAL SODIUM | CHEMBL1200982 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BUTALBITAL | CHEMBL454 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| CENOBAMATE | CHEMBL3989949 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
1 to 10 of 76
See all 76 drugsTrials1,164
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07602400 | SEVOFLURANE | ClinicalTrials.gov | ||
| NCT07602400 | PROPOFOL | ClinicalTrials.gov | ||
| NCT07588750 | TOPIRAMATE | ClinicalTrials.gov | ||
| NCT07584902 | CIPEPOFOL | ClinicalTrials.gov | ||
| NCT07584902 | PROPOFOL | ClinicalTrials.gov | ||
| NCT07569198 | MIDAZOLAM | PHASE2 | ClinicalTrials.gov | |
| NCT07568938 | DESFLURANE | ClinicalTrials.gov | ||
| NCT07560878 | LORAZEPAM | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT07532733 | PROPOFOL | ClinicalTrials.gov | ||
| NCT07513870 | SEVOFLURANE | ClinicalTrials.gov |
1 to 10 of 1,164
See all 1,164 trialsNIH grants643
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GABRG3 papers | Newest fiscal year |
|---|---|---|---|
| U10AA008401 | Collaborative Study on the Genetics of Alcoholism (COGA). | 14 | 2025 |
| ZIAAA000301 | Integrative genetics of behavior with high throughput technologies | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 2 | 2025 |
| P30CA138292 | Winship Cancer Institute Cancer Center Support Grant | 2 | 2025 |
| P30ES019776 | HERCULES: Exposome Research Center | 2 | 2025 |
| P60AA007611 | Center on Genetic Determinants of Alcohol Ingestion and Responses to Alcohol | 2 | 2025 |
| R28AA012725 | Brain Tissue Resource Center for Alcohol Research | 2 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 2 | 2025 |
| UL1TR001881 | UCLA Clinical and Translational Science Institute | 2 | 2025 |
1 to 10 of 643Source NIH's project files
See all 643 nih grantsPapers470
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Sleep disruption and neuropsychiatric features in Angelman syndrome: insights into underlying neurobiology. | Sleep Med | 2026 | 42607587 | PubTator, text mining | PubMed |
| Genomics of Complex Neurodevelopmental Disorders with Variable Epilepsy Phenotypes: A Clinical Review of Dup15q Syndrome. | Genes (Basel) | 2026 | 41751547 | PubTator, text mining | PubMed |
| Broken adaptive ridge method for variable selection in generalized partly linear models with application to the coronary artery disease data. | J Comput Math Data Sci | 2025 | 41626258 | PubTator, text mining | PubMed |
| Distinctive GABA A receptor subunit expression modulates cell specific EMT and functional responses in glioblastoma breast and ovarian cancer. | Sci Rep | 2025 | 41023051 | PubTator, text mining | PubMed |
| A stem cell-based toolkit to model Angelman syndrome caused by paternal uniparental disomy of chromosome 15. | Hum Cell | 2025 | 40956516 | PubTator, text mining | PubMed |
| Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. | Nat Commun | 2025 | 40835596 | PubTator, text mining | PubMed |
| Blood Plasma Methylated DNA Markers in the Detection of Lymphoma: Discovery, Validation, and Clinical Pilot. | Am J Hematol | 2025 | 39564730 | PubTator, text mining | PubMed |
| Towards a precision approach to anesthetic/analgesic immunomodulation in cancer. | Front Anesthesiol | 2024 | 40909996 | PubTator, text mining | PubMed |
| Bridging chemical structure and conceptual knowledge enables accurate prediction of compound-protein interaction. | BMC Biol | 2024 | 39468510 | PubTator, text mining | PubMed |
| Drug-target interaction prediction through fine-grained selection and bidirectional random walk methodology. | Sci Rep | 2024 | 39103483 | PubTator, text mining | PubMed |
1 to 10 of 470
See all 470 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2567
GET https://conductscience.org/api/genes/v1/2567/patents?page=2