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Gene · 2567

GABRG3: gamma-aminobutyric acid type A receptor subunit gamma3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GABRG3: gamma-aminobutyric acid type A receptor subunit gamma3. Genes, record 2567. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2567

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Gene

Symbol
GABRG3
HGNC
Name
gamma-aminobutyric acid type A receptor subunit gamma3
HGNC
NCBI Gene ID
2567
NCBI Gene
HGNC ID
HGNC:4088
HGNC
Ensembl
ENSG00000182256
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99928Gamma-aminobutyric acid receptor subunit gamma-34670Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447270Q99928Espacenet
EP 4650780 A22025-11-1918386Q99928Espacenet
EP 4641201 A22025-10-2922874Q99928Espacenet
JP 2025147176 A2025-10-065696Q99928Espacenet
JP 2025529142 A2025-09-041665Q99928Espacenet
JP 2025529142 A2025-09-046442Q99928Espacenet
US 12371689 B22025-07-291665Q99928Espacenet
US 12371689 B22025-07-296442Q99928Espacenet
JP 2025517969 A2025-06-1222874Q99928Espacenet
JP 2025517970 A2025-06-1218386Q99928Espacenet

1 to 10 of 32

See all 32 patents

Drugs76

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABP-700CHEMBL4297255GABA-A receptor; anion channel agonistAGONISTChEMBL
ACAMPROSATECHEMBL1201293GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ACAMPROSATE CALCIUMCHEMBL2068724GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ADIPIPLONCHEMBL2103791GABA-A receptor; anion channel partial agonistPARTIAL AGONISTChEMBL
ALPRAZOLAMCHEMBL661GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BREXANOLONECHEMBL207538GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITALCHEMBL449GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITAL SODIUMCHEMBL1200982GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTALBITALCHEMBL454GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
CENOBAMATECHEMBL3989949GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL

1 to 10 of 76

See all 76 drugs

Trials1,164

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants643

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGABRG3 papersNewest fiscal year
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).142025
ZIAAA000301Integrative genetics of behavior with high throughput technologies32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center22025
P30CA138292Winship Cancer Institute Cancer Center Support Grant22025
P30ES019776HERCULES: Exposome Research Center22025
P60AA007611Center on Genetic Determinants of Alcohol Ingestion and Responses to Alcohol22025
R28AA012725Brain Tissue Resource Center for Alcohol Research22025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)22025
UL1TR001881UCLA Clinical and Translational Science Institute22025

1 to 10 of 643Source NIH's project files

See all 643 nih grants

Papers470

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Sleep disruption and neuropsychiatric features in Angelman syndrome: insights into underlying neurobiology.Sleep Med202642607587PubTator, text miningPubMed
Genomics of Complex Neurodevelopmental Disorders with Variable Epilepsy Phenotypes: A Clinical Review of Dup15q Syndrome.Genes (Basel)202641751547PubTator, text miningPubMed
Broken adaptive ridge method for variable selection in generalized partly linear models with application to the coronary artery disease data.J Comput Math Data Sci202541626258PubTator, text miningPubMed
Distinctive GABA A receptor subunit expression modulates cell specific EMT and functional responses in glioblastoma breast and ovarian cancer.Sci Rep202541023051PubTator, text miningPubMed
A stem cell-based toolkit to model Angelman syndrome caused by paternal uniparental disomy of chromosome 15.Hum Cell202540956516PubTator, text miningPubMed
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics.Nat Commun202540835596PubTator, text miningPubMed
Blood Plasma Methylated DNA Markers in the Detection of Lymphoma: Discovery, Validation, and Clinical Pilot.Am J Hematol202539564730PubTator, text miningPubMed
Towards a precision approach to anesthetic/analgesic immunomodulation in cancer.Front Anesthesiol202440909996PubTator, text miningPubMed
Bridging chemical structure and conceptual knowledge enables accurate prediction of compound-protein interaction.BMC Biol202439468510PubTator, text miningPubMed
Drug-target interaction prediction through fine-grained selection and bidirectional random walk methodology.Sci Rep202439103483PubTator, text miningPubMed

1 to 10 of 470

See all 470 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2567

GET https://conductscience.org/api/genes/v1/2567/patents?page=2