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Gene · 2568

GABRP: gamma-aminobutyric acid type A receptor subunit pi

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GABRP: gamma-aminobutyric acid type A receptor subunit pi. Genes, record 2568. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2568

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Gene

Symbol
GABRP
HGNC
Name
gamma-aminobutyric acid type A receptor subunit pi
HGNC
NCBI Gene ID
2568
NCBI Gene
HGNC ID
HGNC:4089
HGNC
Ensembl
ENSG00000094755
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00591Gamma-aminobutyric acid receptor subunit pi4402Ensembl, GeneID, HGNC

Source UniProt

Patents57

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447271O00591Espacenet
JP 2026004568 A2026-01-1447273O00591Espacenet
EP 4650780 A22025-11-192458O00591Espacenet
JP 2025147176 A2025-10-065706O00591Espacenet
JP 2025147176 A2025-10-065707O00591Espacenet
JP 2025529142 A2025-09-041666O00591Espacenet
JP 2025529142 A2025-09-046443O00591Espacenet
US 12371689 B22025-07-291666O00591Espacenet
US 12371689 B22025-07-296443O00591Espacenet
JP 2025517970 A2025-06-122458O00591Espacenet

1 to 10 of 57

See all 57 patents

Drugs76

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABP-700CHEMBL4297255GABA-A receptor; anion channel agonistAGONISTChEMBL
ACAMPROSATECHEMBL1201293GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ACAMPROSATE CALCIUMCHEMBL2068724GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ADIPIPLONCHEMBL2103791GABA-A receptor; anion channel partial agonistPARTIAL AGONISTChEMBL
ALPRAZOLAMCHEMBL661GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BREXANOLONECHEMBL207538GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITALCHEMBL449GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITAL SODIUMCHEMBL1200982GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTALBITALCHEMBL454GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
CENOBAMATECHEMBL3989949GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL

1 to 10 of 76

See all 76 drugs

Trials1,164

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants341

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGABRP papersNewest fiscal year
UL1TR001863Yale Clinical and Translational Science Award32025
P30CA006516Dana-Farber/Harvard Cancer Center22025
P30CA043703Case Comprehensive Cancer Center Support Grant22025
P30CA118100University of New Mexico Cancer Center Support Grant22025
R01DE023222Mutations and Target Genes in Adenoid Cystic Carcinoma22025
R01HD094937Modeling Normal and Abnormal Trophoblasts22025
T32GM145304Cellular Biotechnology Training Program (CBTP) - Years 31-3522025
ZIAAA000301Integrative genetics of behavior with high throughput technologies22025
K12DA000167Clinician Scientist Training Program (CSTP)12025
K12GM106996IRACDA at UCLA12025

1 to 10 of 341Source NIH's project files

See all 341 nih grants

Papers396

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and Functional Characteristics of NR5A1 Gene Variant in Patients with 46,XY Disorders of Sex Development.Genes (Basel)202642792964PubTator, text miningPubMed
Risk Factors and Biomarkers for Immune Checkpoint Inhibitor-mediated Hepatotoxicity: Emerging Insights and Future Perspectives.J Clin Transl Hepatol202641810106PubTator, text miningPubMed
Essential tremor: Family-based sequencing suggests involvement of neuronal and metabolic pathways.Parkinsonism Relat Disord202641762786PubTator, text miningPubMed
Targeted biologics for TNBC: Advances in nanobodies, antibodies, peptides, and aptamers.Mol Ther Oncol202641716468PubTator, text miningPubMed
RNAseq-based meta-analyses revealed tumor suppressor-inducer fusion events in liver, oral, and ovarian cancer in the Indian population: a cancer cell surviving mechanism.Nucleosides Nucleotides Nucleic Acids202641661231PubTator, text miningPubMed
The influence of neuro-tumor interactions on tumorigenesis and therapeutic response.Exp Hematol Oncol202641645346PubTator, text miningPubMed
Single-Cell RNA Sequencing and Bulk RNA Sequencing Revealed the Interplay Between Intratumoral Heterogeneity and the Tumor Microenvironment in Breast Cancer.Cancer Med202641635010PubTator, text miningPubMed
Shedding light on the function of autophagy in complicated pregnancies.Cell Death Dis202641507150PubTator, text miningPubMed
Children with Autism Spectrum Disorder and Chronic Gastrointestinal Symptoms Have Alterations in Intestinal Neurotransmitter Pathways.Dig Dis Sci202641504861PubTator, text miningPubMed
Multi-omics unravel heterogeneity of glucose metabolism reprogramming in gastric cancer.Clin Exp Med202541249595PubTator, text miningPubMed

1 to 10 of 396

See all 396 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2568

GET https://conductscience.org/api/genes/v1/2568/patents?page=2